3-Bromopyruvate sensitizes human breast cancer cells to TRAIL-induced apoptosis via the phosphorylated AMPK-mediated upregulation of DR5

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Previous studies have indicated that the sensitivity of breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis is associated with the expression of death receptors on the cell membrane. However, drug resistance limits the use of TRAIL in cancer thera...

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Detalles Bibliográficos
Autores principales: Chen, Yuzhong, Wei, Li, Zhang, Xiaojing, Liu, Xianfu, Chen, Yansong, Zhang, Song, Zhou, Lanzhu, Li, Qixiang, Pan, Qiong, Zhao, Surong, Liu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151892/
https://www.ncbi.nlm.nih.gov/pubmed/30132536
http://dx.doi.org/10.3892/or.2018.6644
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