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Open questions: CRISPR biology

CRISPR-Cas systems, the purveyors of adaptive immunity in archaea and bacteria and sources of the new generation of genome engineering tools, have been studied in exquisite molecular detail. However, when it comes to biological functions, ecology, and evolution of CRISPR-Cas, many more intriguing qu...

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Detalles Bibliográficos
Autor principal: Koonin, Eugene V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151929/
https://www.ncbi.nlm.nih.gov/pubmed/30244670
http://dx.doi.org/10.1186/s12915-018-0565-9
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author Koonin, Eugene V.
author_facet Koonin, Eugene V.
author_sort Koonin, Eugene V.
collection PubMed
description CRISPR-Cas systems, the purveyors of adaptive immunity in archaea and bacteria and sources of the new generation of genome engineering tools, have been studied in exquisite molecular detail. However, when it comes to biological functions, ecology, and evolution of CRISPR-Cas, many more intriguing questions remain than there are answers.
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spelling pubmed-61519292018-09-26 Open questions: CRISPR biology Koonin, Eugene V. BMC Biol Comment CRISPR-Cas systems, the purveyors of adaptive immunity in archaea and bacteria and sources of the new generation of genome engineering tools, have been studied in exquisite molecular detail. However, when it comes to biological functions, ecology, and evolution of CRISPR-Cas, many more intriguing questions remain than there are answers. BioMed Central 2018-09-24 /pmc/articles/PMC6151929/ /pubmed/30244670 http://dx.doi.org/10.1186/s12915-018-0565-9 Text en © Koonin et al. 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Comment
Koonin, Eugene V.
Open questions: CRISPR biology
title Open questions: CRISPR biology
title_full Open questions: CRISPR biology
title_fullStr Open questions: CRISPR biology
title_full_unstemmed Open questions: CRISPR biology
title_short Open questions: CRISPR biology
title_sort open questions: crispr biology
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151929/
https://www.ncbi.nlm.nih.gov/pubmed/30244670
http://dx.doi.org/10.1186/s12915-018-0565-9
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