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Open questions: CRISPR biology
CRISPR-Cas systems, the purveyors of adaptive immunity in archaea and bacteria and sources of the new generation of genome engineering tools, have been studied in exquisite molecular detail. However, when it comes to biological functions, ecology, and evolution of CRISPR-Cas, many more intriguing qu...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151929/ https://www.ncbi.nlm.nih.gov/pubmed/30244670 http://dx.doi.org/10.1186/s12915-018-0565-9 |
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author | Koonin, Eugene V. |
author_facet | Koonin, Eugene V. |
author_sort | Koonin, Eugene V. |
collection | PubMed |
description | CRISPR-Cas systems, the purveyors of adaptive immunity in archaea and bacteria and sources of the new generation of genome engineering tools, have been studied in exquisite molecular detail. However, when it comes to biological functions, ecology, and evolution of CRISPR-Cas, many more intriguing questions remain than there are answers. |
format | Online Article Text |
id | pubmed-6151929 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-61519292018-09-26 Open questions: CRISPR biology Koonin, Eugene V. BMC Biol Comment CRISPR-Cas systems, the purveyors of adaptive immunity in archaea and bacteria and sources of the new generation of genome engineering tools, have been studied in exquisite molecular detail. However, when it comes to biological functions, ecology, and evolution of CRISPR-Cas, many more intriguing questions remain than there are answers. BioMed Central 2018-09-24 /pmc/articles/PMC6151929/ /pubmed/30244670 http://dx.doi.org/10.1186/s12915-018-0565-9 Text en © Koonin et al. 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Comment Koonin, Eugene V. Open questions: CRISPR biology |
title | Open questions: CRISPR biology |
title_full | Open questions: CRISPR biology |
title_fullStr | Open questions: CRISPR biology |
title_full_unstemmed | Open questions: CRISPR biology |
title_short | Open questions: CRISPR biology |
title_sort | open questions: crispr biology |
topic | Comment |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151929/ https://www.ncbi.nlm.nih.gov/pubmed/30244670 http://dx.doi.org/10.1186/s12915-018-0565-9 |
work_keys_str_mv | AT koonineugenev openquestionscrisprbiology |