Histone variants H2A.Z and H3.3 coordinately regulate PRC2-dependent H3K27me3 deposition and gene expression regulation in mES cells

BACKGROUND: The hierarchical organization of eukaryotic chromatin plays a central role in gene regulation, by controlling the extent to which the transcription machinery can access DNA. The histone variants H3.3 and H2A.Z have recently been identified as key regulatory players in this process, but t...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yan, Long, Haizhen, Yu, Juan, Dong, Liping, Wassef, Michel, Zhuo, Baowen, Li, Xia, Zhao, Jicheng, Wang, Min, Liu, Cuifang, Wen, Zengqi, Chang, Luyuan, Chen, Ping, Wang, Qian-fei, Xu, Xueqing, Margueron, Raphael, Li, Guohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151936/
https://www.ncbi.nlm.nih.gov/pubmed/30249243
http://dx.doi.org/10.1186/s12915-018-0568-6

Ejemplares similares

Ejemplares similares