Cargando…

An Efficient Synthesis of Arylated Pyridines from Conjugated Acetylenes and Substituted Benzylamines Catalyzed by Base

An efficient base-catalyzed synthesis of arylated pyridines has been disclosed. This reaction involving conjugated acetylenes and substituted benzylamines proceeded smoothly, giving rise to tri-aryl substituted pyridines which are biologically relevant compounds in good to excellent yields in N,N-di...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Mengping, Chen, Bo, Zhu, Qiming, Jin, Hua, Peng, Qiuling, Kang, Yanping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152059/ https://www.ncbi.nlm.nih.gov/pubmed/28758981 http://dx.doi.org/10.3390/molecules22081277

Ejemplares similares

Substituted Aryl Benzylamines as Potent and Selective Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 3
por: Vicker, Nigel, et al.
Publicado: (2021)

Nickel-catalyzed enantioselective arylation of pyridine
por: Lutz, J. Patrick, et al.
Publicado: (2016)

Catalytic enantioselective synthesis of tetrasubstituted chromanones via palladium-catalyzed asymmetric conjugate arylation using chiral pyridine-dihydroisoquinoline ligands
por: Baek, Doohyun, et al.
Publicado: (2020)

Tandem Pd-Catalyzed Cyclization/Coupling of Non-Terminal Acetylenic Activated Methylenes with (Hetero)Aryl Bromides †
por: Błocka, Aleksandra, et al.
Publicado: (2022)

Dual Copper- and Aldehyde-Catalyzed Transient C–H Sulfonylation of Benzylamines
por: Higham, Joe I., et al.
Publicado: (2023)

Nickel-catalyzed arylative substitution of homoallylic alcohols
por: Tran, Hai N., et al.
Publicado: (2022)

In(III) and Hf(IV) Triflate-Catalyzed Hydration and Catalyst-free Hydrohalogenation of Aryl Acetylenes in Liquid Sulfur Dioxide
por: Suta, Krista, et al.
Publicado: (2018)

NiH-catalyzed asymmetric hydroarylation of N-acyl enamines to chiral benzylamines
por: He, Yuli, et al.
Publicado: (2021)

Synthesis of 1,5-Substituted Pyrrolidin-2-ones from Donor–Acceptor Cyclopropanes and Anilines/Benzylamines
por: Boichenko, Maksim A., et al.
Publicado: (2022)

A palladium-catalyzed synthesis of (hetero)aryl-substituted imidazoles from aryl halides, imines and carbon monoxide
por: Tjutrins, Jevgenijs, et al.
Publicado: (2017)

Efficient Palladium-Catalyzed Synthesis of 2-Aryl Propionic Acids
por: Neumann, Helfried, et al.
Publicado: (2020)

Cu-catalyzed carboboration of acetylene with Michael acceptors
por: Cheng, Tairan, et al.
Publicado: (2022)

Efficient Cu-catalyzed intramolecular O-arylation for synthesis of benzoxazoles in water
por: Tang, Yanling, et al.
Publicado: (2020)

Design of carbon supports for metal-catalyzed acetylene hydrochlorination
por: Kaiser, Selina K., et al.
Publicado: (2021)

Gold(I)-Catalyzed Intermolecular Aryloxyvinylation with Acetylene Gas
por: Medina-Gil, Tania, et al.
Publicado: (2023)

Intracellular DNA Damage by Lysine-Acetylene Conjugates
por: Yang, Wang-Yong, et al.
Publicado: (2010)

Mechanistic Investigations and Substrate Scope Evaluation of Ruthenium-Catalyzed Direct sp(3) Arylation of Benzylic Positions Directed by 3-Substituted Pyridines
por: Dastbaravardeh, Navid, et al.
Publicado: (2012)

Hetero-Diels–Alder reactions of hetaryl and aryl thioketones with acetylenic dienophiles
por: Mlostoń, Grzegorz, et al.
Publicado: (2015)

Ni-catalyzed asymmetric hydrogenation of N-aryl imino esters for the efficient synthesis of chiral α-aryl glycines
por: Liu, Dan, et al.
Publicado: (2020)

Efficient synthesis of 5-substituted 2-aryl-6-cyanoindolizines via nucleophilic substitution reactions
por: Babaev, Eugene V, et al.
Publicado: (2005)

Highly Efficient and Reusable Copper-Catalyzed N-Arylation of Nitrogen-Containing Heterocycles with Aryl Halides
por: Kim, A Young, et al.
Publicado: (2009)

Synthesis of vinyl-substituted alcohols using acetylene as a C2 building block
por: Lin, Zhicong, et al.
Publicado: (2022)

Base-catalyzed synthesis of aryl amides from aryl azides and aldehydes
por: Xie, Sheng, et al.
Publicado: (2016)

Collective synthesis of acetylenic pharmaceuticals via enantioselective Nickel/Lewis acid-catalyzed propargylic alkylation
por: Chang, Xihao, et al.
Publicado: (2021)

Experimental Characterization of the Pyridine:Acetylene Co-crystal and Implications for Titan’s Surface
por: Czaplinski, Ellen C., et al.
Publicado: (2023)

Evidence of bifunctionality of carbons and metal atoms in catalyzed acetylene hydrochlorination
por: Giulimondi, Vera, et al.
Publicado: (2023)

Design, synthesis and cholinesterase inhibitory properties of new oxazole benzylamine derivatives
por: Šagud, Ivana, et al.
Publicado: (2020)

Transition Metal Catalyzed Synthesis of Aryl Sulfides
por: Eichman, Chad C., et al.
Publicado: (2011)

One-Pot Synthesis of 1-Aryl-3-trifluoromethylpyrazoles Using Nitrile Imines and Mercaptoacetaldehyde As a Surrogate of Acetylene
por: Świątek, Kamil, et al.
Publicado: (2023)

Deaminative coupling of benzylamines and arylboronic acids
por: Sirvinskaite, Giedre, et al.
Publicado: (2023)

Regio- and chemoselective Csp(3)–H arylation of benzylamines by single electron transfer/hydrogen atom transfer synergistic catalysis
por: Ide, Takafumi, et al.
Publicado: (2018)

Natural dolomitic limestone-catalyzed synthesis of benzimidazoles, dihydropyrimidinones, and highly substituted pyridines under ultrasound irradiation
por: Godugu, Kumar, et al.
Publicado: (2020)

Cationic palladium(ii)-catalyzed synthesis of substituted pyridines from α,β-unsaturated oxime ethers
por: Yamada, Takahiro, et al.
Publicado: (2022)

Unveiling meta-Alkyloxy/-Silyloxy-Substituted N-Aryl PNP Ligands for Efficient Cr-Catalyzed Ethylene Tetramerization
por: Barman, Samir, et al.
Publicado: (2023)

Iridium-Catalyzed C–H Borylation of CF(3)-Substituted Pyridines
por: Shahzadi, Hafiza Tayyaba, et al.
Publicado: (2022)

Correction: Synthesis of vinyl-substituted alcohols using acetylene as a C2 building block
por: Lin, Zhicong, et al.
Publicado: (2023)

A Well-Defined {[(PhCH(2)O)(2)P(CH(3))(2)CHNCH(CH(3))(2)](2)PdCl(2)} Complex Catalyzed Hiyama Coupling of Aryl Bromides with Arylsilanes
por: Guo, Mengping, et al.
Publicado: (2016)

Substituted Dihydropyridine Synthesis by Dearomatization of Pyridines
por: Heusler, Arne, et al.
Publicado: (2021)

Synthesis of 3-aryl-2-phosphinoimidazo[1,2-a]pyridine ligands for use in palladium-catalyzed cross-coupling reactions
por: Tran, Ryan Q., et al.
Publicado: (2019)

Efficient Palladium‐Catalyzed Aerobic Arylative Carbocyclization of Enallenynes
por: Liu, Jie, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_li7prd28cd7m37i9a2f51ib2ui