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Synthesis, Antitumor Evaluation and Molecular Docking of New Morpholine Based Heterocycles

A series of new morpholinylchalcones was prepared and then used as building blocks for constructing a series of 7-morpholino-2-thioxo-2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-ones via their reaction with 6-aminothiouracil. The latter thiones reacted with the appropriate hydrazonoyl chloride to give t...

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Detalles Bibliográficos
Autores principales: Muhammad, Zeinab A., Edrees, Mastoura M., Faty, Rasha A. M., Gomha, Sobhi M., Alterary, Seham S., Mabkhot, Yahia N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152077/
https://www.ncbi.nlm.nih.gov/pubmed/28726760
http://dx.doi.org/10.3390/molecules22071211