NMR Insights into the Structure-Function Relationships in the Binding of Melanocortin Analogues to the MC1R Receptor

Linear and cyclic analogues of the α-melanocyte stimulating hormone (α-MSH) targeting the human melanocortin receptor 1 (MC1R) are of pharmacological interest for detecting and treating melanoma. The central sequence of α-MSH (His-Phe-Arg-Trp) has been identified as being essential for receptor bind...

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Detalles Bibliográficos
Autores principales: Morais, Maurício, Zamora-Carreras, Héctor, Raposinho, Paula D., Oliveira, Maria Cristina, Pantoja-Uceda, David, Correia, João D. G., Jiménez, M. Angeles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152105/
https://www.ncbi.nlm.nih.gov/pubmed/28714883
http://dx.doi.org/10.3390/molecules22071189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152105/
https://www.ncbi.nlm.nih.gov/pubmed/28714883
http://dx.doi.org/10.3390/molecules22071189

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