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Trehalose Inhibits A53T Mutant α-Synuclein Overexpression and Neurotoxicity in Transduced PC12 Cells

Fibrillar accumulation of A53T mutant α-synuclein (A53T-AS) in Lewy bodies is a symptom of Parkinsonism. Inhibitions of the overexpression and fibrillar aggregation of α-synuclein (AS) in vivo could be a promising strategy for treating Parkinson’s disease (PD). In this study, at concentrations lower...

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Detalles Bibliográficos
Autores principales:	Zhao, Juan, Zhi, Xiuling, Pan, Luanfeng, Zhou, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152154/ https://www.ncbi.nlm.nih.gov/pubmed/28786917 http://dx.doi.org/10.3390/molecules22081293

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