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Retrospective clinical case series study in 2017 identifies Plasmodium knowlesi as most frequent Plasmodium species in returning travellers from Thailand to Germany
Febrile illnesses are common in travellers returning from south-east Asia. However, malaria is a rare diagnosis in this population. A series of Plasmodium knowlesi infections was noted in German travellers returning from Thailand since 2012. Infectious disease and tropical medicine facilities regist...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Centre for Disease Prevention and Control (ECDC)
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152204/ https://www.ncbi.nlm.nih.gov/pubmed/30043723 http://dx.doi.org/10.2807/1560-7917.ES.2018.23.29.1700619 |
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author | Froeschl, Guenter Nothdurft, Hans Dieter von Sonnenburg, Frank Bretzel, Gisela Polanetz, Roman Kroidl, Inge Seilmaier, Michael Orth, Hans Martin Jordan, Sabine Kremsner, Peter Vygen-Bonnet, Sabine Pritsch, Michael Hoelscher, Michael Rothe, Camilla |
author_facet | Froeschl, Guenter Nothdurft, Hans Dieter von Sonnenburg, Frank Bretzel, Gisela Polanetz, Roman Kroidl, Inge Seilmaier, Michael Orth, Hans Martin Jordan, Sabine Kremsner, Peter Vygen-Bonnet, Sabine Pritsch, Michael Hoelscher, Michael Rothe, Camilla |
author_sort | Froeschl, Guenter |
collection | PubMed |
description | Febrile illnesses are common in travellers returning from south-east Asia. However, malaria is a rare diagnosis in this population. A series of Plasmodium knowlesi infections was noted in German travellers returning from Thailand since 2012. Infectious disease and tropical medicine facilities registered by the German Society for Tropical Medicine and International Health were contacted in March 2017, and asked to report previous P. knowlesi cases. In addition, surveillance data from the Robert Koch-Institute were analysed. The facilities reported a total of six P. knowlesi-positive cases, all were returning travellers from Thailand. The P. knowlesi-positive cases made up 6/9 of all diagnosed malaria cases imported from Thailand in the time period 2012 to 2017. In 4/5 of cases where a malaria rapid diagnostic test had been applied it revealed a negative result. P. knowlesi is an important differential diagnosis in travellers returning from south-east Asia with itineraries that include Thailand. This study highlights the importance of this Plasmodium species in this patient subgroup. Whenever malaria is suspected in a returning traveller from Thailand, P. knowlesi should be taken into consideration and a differential PCR be executed as currently the unequivocal diagnosis of P. knowlesi is based on nuclear amplification techniques. |
format | Online Article Text |
id | pubmed-6152204 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | European Centre for Disease Prevention and Control (ECDC) |
record_format | MEDLINE/PubMed |
spelling | pubmed-61522042018-10-12 Retrospective clinical case series study in 2017 identifies Plasmodium knowlesi as most frequent Plasmodium species in returning travellers from Thailand to Germany Froeschl, Guenter Nothdurft, Hans Dieter von Sonnenburg, Frank Bretzel, Gisela Polanetz, Roman Kroidl, Inge Seilmaier, Michael Orth, Hans Martin Jordan, Sabine Kremsner, Peter Vygen-Bonnet, Sabine Pritsch, Michael Hoelscher, Michael Rothe, Camilla Euro Surveill Surveillance and Outbreak Report Febrile illnesses are common in travellers returning from south-east Asia. However, malaria is a rare diagnosis in this population. A series of Plasmodium knowlesi infections was noted in German travellers returning from Thailand since 2012. Infectious disease and tropical medicine facilities registered by the German Society for Tropical Medicine and International Health were contacted in March 2017, and asked to report previous P. knowlesi cases. In addition, surveillance data from the Robert Koch-Institute were analysed. The facilities reported a total of six P. knowlesi-positive cases, all were returning travellers from Thailand. The P. knowlesi-positive cases made up 6/9 of all diagnosed malaria cases imported from Thailand in the time period 2012 to 2017. In 4/5 of cases where a malaria rapid diagnostic test had been applied it revealed a negative result. P. knowlesi is an important differential diagnosis in travellers returning from south-east Asia with itineraries that include Thailand. This study highlights the importance of this Plasmodium species in this patient subgroup. Whenever malaria is suspected in a returning traveller from Thailand, P. knowlesi should be taken into consideration and a differential PCR be executed as currently the unequivocal diagnosis of P. knowlesi is based on nuclear amplification techniques. European Centre for Disease Prevention and Control (ECDC) 2018-07-19 /pmc/articles/PMC6152204/ /pubmed/30043723 http://dx.doi.org/10.2807/1560-7917.ES.2018.23.29.1700619 Text en This article is copyright of The Authors, 2018. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made. |
spellingShingle | Surveillance and Outbreak Report Froeschl, Guenter Nothdurft, Hans Dieter von Sonnenburg, Frank Bretzel, Gisela Polanetz, Roman Kroidl, Inge Seilmaier, Michael Orth, Hans Martin Jordan, Sabine Kremsner, Peter Vygen-Bonnet, Sabine Pritsch, Michael Hoelscher, Michael Rothe, Camilla Retrospective clinical case series study in 2017 identifies Plasmodium knowlesi as most frequent Plasmodium species in returning travellers from Thailand to Germany |
title | Retrospective clinical case series study in 2017 identifies Plasmodium knowlesi as most frequent Plasmodium species in returning travellers from Thailand to Germany |
title_full | Retrospective clinical case series study in 2017 identifies Plasmodium knowlesi as most frequent Plasmodium species in returning travellers from Thailand to Germany |
title_fullStr | Retrospective clinical case series study in 2017 identifies Plasmodium knowlesi as most frequent Plasmodium species in returning travellers from Thailand to Germany |
title_full_unstemmed | Retrospective clinical case series study in 2017 identifies Plasmodium knowlesi as most frequent Plasmodium species in returning travellers from Thailand to Germany |
title_short | Retrospective clinical case series study in 2017 identifies Plasmodium knowlesi as most frequent Plasmodium species in returning travellers from Thailand to Germany |
title_sort | retrospective clinical case series study in 2017 identifies plasmodium knowlesi as most frequent plasmodium species in returning travellers from thailand to germany |
topic | Surveillance and Outbreak Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152204/ https://www.ncbi.nlm.nih.gov/pubmed/30043723 http://dx.doi.org/10.2807/1560-7917.ES.2018.23.29.1700619 |
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