Cargando…

Retrospective clinical case series study in 2017 identifies Plasmodium knowlesi as most frequent Plasmodium species in returning travellers from Thailand to Germany

Febrile illnesses are common in travellers returning from south-east Asia. However, malaria is a rare diagnosis in this population. A series of Plasmodium knowlesi infections was noted in German travellers returning from Thailand since 2012. Infectious disease and tropical medicine facilities regist...

Descripción completa

Detalles Bibliográficos
Autores principales: Froeschl, Guenter, Nothdurft, Hans Dieter, von Sonnenburg, Frank, Bretzel, Gisela, Polanetz, Roman, Kroidl, Inge, Seilmaier, Michael, Orth, Hans Martin, Jordan, Sabine, Kremsner, Peter, Vygen-Bonnet, Sabine, Pritsch, Michael, Hoelscher, Michael, Rothe, Camilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152204/
https://www.ncbi.nlm.nih.gov/pubmed/30043723
http://dx.doi.org/10.2807/1560-7917.ES.2018.23.29.1700619
_version_ 1783357317780078592
author Froeschl, Guenter
Nothdurft, Hans Dieter
von Sonnenburg, Frank
Bretzel, Gisela
Polanetz, Roman
Kroidl, Inge
Seilmaier, Michael
Orth, Hans Martin
Jordan, Sabine
Kremsner, Peter
Vygen-Bonnet, Sabine
Pritsch, Michael
Hoelscher, Michael
Rothe, Camilla
author_facet Froeschl, Guenter
Nothdurft, Hans Dieter
von Sonnenburg, Frank
Bretzel, Gisela
Polanetz, Roman
Kroidl, Inge
Seilmaier, Michael
Orth, Hans Martin
Jordan, Sabine
Kremsner, Peter
Vygen-Bonnet, Sabine
Pritsch, Michael
Hoelscher, Michael
Rothe, Camilla
author_sort Froeschl, Guenter
collection PubMed
description Febrile illnesses are common in travellers returning from south-east Asia. However, malaria is a rare diagnosis in this population. A series of Plasmodium knowlesi infections was noted in German travellers returning from Thailand since 2012. Infectious disease and tropical medicine facilities registered by the German Society for Tropical Medicine and International Health were contacted in March 2017, and asked to report previous P. knowlesi cases. In addition, surveillance data from the Robert Koch-Institute were analysed. The facilities reported a total of six P. knowlesi-positive cases, all were returning travellers from Thailand. The P. knowlesi-positive cases made up 6/9 of all diagnosed malaria cases imported from Thailand in the time period 2012 to 2017. In 4/5 of cases where a malaria rapid diagnostic test had been applied it revealed a negative result. P. knowlesi is an important differential diagnosis in travellers returning from south-east Asia with itineraries that include Thailand. This study highlights the importance of this Plasmodium species in this patient subgroup. Whenever malaria is suspected in a returning traveller from Thailand, P. knowlesi should be taken into consideration and a differential PCR be executed as currently the unequivocal diagnosis of P. knowlesi is based on nuclear amplification techniques.
format Online
Article
Text
id pubmed-6152204
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher European Centre for Disease Prevention and Control (ECDC)
record_format MEDLINE/PubMed
spelling pubmed-61522042018-10-12 Retrospective clinical case series study in 2017 identifies Plasmodium knowlesi as most frequent Plasmodium species in returning travellers from Thailand to Germany Froeschl, Guenter Nothdurft, Hans Dieter von Sonnenburg, Frank Bretzel, Gisela Polanetz, Roman Kroidl, Inge Seilmaier, Michael Orth, Hans Martin Jordan, Sabine Kremsner, Peter Vygen-Bonnet, Sabine Pritsch, Michael Hoelscher, Michael Rothe, Camilla Euro Surveill Surveillance and Outbreak Report Febrile illnesses are common in travellers returning from south-east Asia. However, malaria is a rare diagnosis in this population. A series of Plasmodium knowlesi infections was noted in German travellers returning from Thailand since 2012. Infectious disease and tropical medicine facilities registered by the German Society for Tropical Medicine and International Health were contacted in March 2017, and asked to report previous P. knowlesi cases. In addition, surveillance data from the Robert Koch-Institute were analysed. The facilities reported a total of six P. knowlesi-positive cases, all were returning travellers from Thailand. The P. knowlesi-positive cases made up 6/9 of all diagnosed malaria cases imported from Thailand in the time period 2012 to 2017. In 4/5 of cases where a malaria rapid diagnostic test had been applied it revealed a negative result. P. knowlesi is an important differential diagnosis in travellers returning from south-east Asia with itineraries that include Thailand. This study highlights the importance of this Plasmodium species in this patient subgroup. Whenever malaria is suspected in a returning traveller from Thailand, P. knowlesi should be taken into consideration and a differential PCR be executed as currently the unequivocal diagnosis of P. knowlesi is based on nuclear amplification techniques. European Centre for Disease Prevention and Control (ECDC) 2018-07-19 /pmc/articles/PMC6152204/ /pubmed/30043723 http://dx.doi.org/10.2807/1560-7917.ES.2018.23.29.1700619 Text en This article is copyright of The Authors, 2018. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Surveillance and Outbreak Report
Froeschl, Guenter
Nothdurft, Hans Dieter
von Sonnenburg, Frank
Bretzel, Gisela
Polanetz, Roman
Kroidl, Inge
Seilmaier, Michael
Orth, Hans Martin
Jordan, Sabine
Kremsner, Peter
Vygen-Bonnet, Sabine
Pritsch, Michael
Hoelscher, Michael
Rothe, Camilla
Retrospective clinical case series study in 2017 identifies Plasmodium knowlesi as most frequent Plasmodium species in returning travellers from Thailand to Germany
title Retrospective clinical case series study in 2017 identifies Plasmodium knowlesi as most frequent Plasmodium species in returning travellers from Thailand to Germany
title_full Retrospective clinical case series study in 2017 identifies Plasmodium knowlesi as most frequent Plasmodium species in returning travellers from Thailand to Germany
title_fullStr Retrospective clinical case series study in 2017 identifies Plasmodium knowlesi as most frequent Plasmodium species in returning travellers from Thailand to Germany
title_full_unstemmed Retrospective clinical case series study in 2017 identifies Plasmodium knowlesi as most frequent Plasmodium species in returning travellers from Thailand to Germany
title_short Retrospective clinical case series study in 2017 identifies Plasmodium knowlesi as most frequent Plasmodium species in returning travellers from Thailand to Germany
title_sort retrospective clinical case series study in 2017 identifies plasmodium knowlesi as most frequent plasmodium species in returning travellers from thailand to germany
topic Surveillance and Outbreak Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152204/
https://www.ncbi.nlm.nih.gov/pubmed/30043723
http://dx.doi.org/10.2807/1560-7917.ES.2018.23.29.1700619
work_keys_str_mv AT froeschlguenter retrospectiveclinicalcaseseriesstudyin2017identifiesplasmodiumknowlesiasmostfrequentplasmodiumspeciesinreturningtravellersfromthailandtogermany
AT nothdurfthansdieter retrospectiveclinicalcaseseriesstudyin2017identifiesplasmodiumknowlesiasmostfrequentplasmodiumspeciesinreturningtravellersfromthailandtogermany
AT vonsonnenburgfrank retrospectiveclinicalcaseseriesstudyin2017identifiesplasmodiumknowlesiasmostfrequentplasmodiumspeciesinreturningtravellersfromthailandtogermany
AT bretzelgisela retrospectiveclinicalcaseseriesstudyin2017identifiesplasmodiumknowlesiasmostfrequentplasmodiumspeciesinreturningtravellersfromthailandtogermany
AT polanetzroman retrospectiveclinicalcaseseriesstudyin2017identifiesplasmodiumknowlesiasmostfrequentplasmodiumspeciesinreturningtravellersfromthailandtogermany
AT kroidlinge retrospectiveclinicalcaseseriesstudyin2017identifiesplasmodiumknowlesiasmostfrequentplasmodiumspeciesinreturningtravellersfromthailandtogermany
AT seilmaiermichael retrospectiveclinicalcaseseriesstudyin2017identifiesplasmodiumknowlesiasmostfrequentplasmodiumspeciesinreturningtravellersfromthailandtogermany
AT orthhansmartin retrospectiveclinicalcaseseriesstudyin2017identifiesplasmodiumknowlesiasmostfrequentplasmodiumspeciesinreturningtravellersfromthailandtogermany
AT jordansabine retrospectiveclinicalcaseseriesstudyin2017identifiesplasmodiumknowlesiasmostfrequentplasmodiumspeciesinreturningtravellersfromthailandtogermany
AT kremsnerpeter retrospectiveclinicalcaseseriesstudyin2017identifiesplasmodiumknowlesiasmostfrequentplasmodiumspeciesinreturningtravellersfromthailandtogermany
AT vygenbonnetsabine retrospectiveclinicalcaseseriesstudyin2017identifiesplasmodiumknowlesiasmostfrequentplasmodiumspeciesinreturningtravellersfromthailandtogermany
AT pritschmichael retrospectiveclinicalcaseseriesstudyin2017identifiesplasmodiumknowlesiasmostfrequentplasmodiumspeciesinreturningtravellersfromthailandtogermany
AT hoelschermichael retrospectiveclinicalcaseseriesstudyin2017identifiesplasmodiumknowlesiasmostfrequentplasmodiumspeciesinreturningtravellersfromthailandtogermany
AT rothecamilla retrospectiveclinicalcaseseriesstudyin2017identifiesplasmodiumknowlesiasmostfrequentplasmodiumspeciesinreturningtravellersfromthailandtogermany