Antioxidant and Anticancer Activities of Essential Oil from Gannan Navel Orange Peel

China is one of the leading producers of citrus in the world. Gannan in Jiangxi Province is the top navel orange producing area in China. In the present study, an essential oil was prepared by cold pressing of Gannan navel orange peel followed by molecular distillation. Its chemical composition was...

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Detalles Bibliográficos
Autores principales: Yang, Chao, Chen, Hui, Chen, Hongli, Zhong, Balian, Luo, Xuzhong, Chun, Jiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152265/
https://www.ncbi.nlm.nih.gov/pubmed/28829378
http://dx.doi.org/10.3390/molecules22081391
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author Yang, Chao
Chen, Hui
Chen, Hongli
Zhong, Balian
Luo, Xuzhong
Chun, Jiong
author_facet Yang, Chao
Chen, Hui
Chen, Hongli
Zhong, Balian
Luo, Xuzhong
Chun, Jiong
author_sort Yang, Chao
collection PubMed
description China is one of the leading producers of citrus in the world. Gannan in Jiangxi Province is the top navel orange producing area in China. In the present study, an essential oil was prepared by cold pressing of Gannan navel orange peel followed by molecular distillation. Its chemical composition was analyzed by GC-MS. Twenty four constituents were identified, representing 97.9% of the total oil. The predominant constituent was limonene (74.6%). The anticancer activities of this orange essential oil, as well as some of its major constituents, were investigated by MTT assay. This essential oil showed a positive effect on the inhibition of the proliferation of a human lung cancer cell line A549 and prostate cancer cell line 22RV-1. Some of the oil constituents displayed high anticancer potential and deserve further study.
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spelling pubmed-61522652018-11-13 Antioxidant and Anticancer Activities of Essential Oil from Gannan Navel Orange Peel Yang, Chao Chen, Hui Chen, Hongli Zhong, Balian Luo, Xuzhong Chun, Jiong Molecules Article China is one of the leading producers of citrus in the world. Gannan in Jiangxi Province is the top navel orange producing area in China. In the present study, an essential oil was prepared by cold pressing of Gannan navel orange peel followed by molecular distillation. Its chemical composition was analyzed by GC-MS. Twenty four constituents were identified, representing 97.9% of the total oil. The predominant constituent was limonene (74.6%). The anticancer activities of this orange essential oil, as well as some of its major constituents, were investigated by MTT assay. This essential oil showed a positive effect on the inhibition of the proliferation of a human lung cancer cell line A549 and prostate cancer cell line 22RV-1. Some of the oil constituents displayed high anticancer potential and deserve further study. MDPI 2017-08-22 /pmc/articles/PMC6152265/ /pubmed/28829378 http://dx.doi.org/10.3390/molecules22081391 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Yang, Chao
Chen, Hui
Chen, Hongli
Zhong, Balian
Luo, Xuzhong
Chun, Jiong
Antioxidant and Anticancer Activities of Essential Oil from Gannan Navel Orange Peel
title Antioxidant and Anticancer Activities of Essential Oil from Gannan Navel Orange Peel
title_full Antioxidant and Anticancer Activities of Essential Oil from Gannan Navel Orange Peel
title_fullStr Antioxidant and Anticancer Activities of Essential Oil from Gannan Navel Orange Peel
title_full_unstemmed Antioxidant and Anticancer Activities of Essential Oil from Gannan Navel Orange Peel
title_short Antioxidant and Anticancer Activities of Essential Oil from Gannan Navel Orange Peel
title_sort antioxidant and anticancer activities of essential oil from gannan navel orange peel
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152265/
https://www.ncbi.nlm.nih.gov/pubmed/28829378
http://dx.doi.org/10.3390/molecules22081391
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