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Combining NMR Spectroscopy and Chemometrics to Monitor Structural Features of Crude Hep-arin
Because of the complexity and global nature of the heparin supply chain, the control of heparin quality during manufacturing steps is essential to ensure the safety of the final active pharmaceutical ingredient (API). For this reason, there is a need to develop consistent analytical methods able to...
Autores principales: | Mauri, Lucio, Marinozzi, Maria, Mazzini, Giulia, Kolinski, Richard E., Karfunkle, Michael, Keire, David A., Guerrini, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152302/ https://www.ncbi.nlm.nih.gov/pubmed/28698456 http://dx.doi.org/10.3390/molecules22071146 |
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