Synthesis of 2H-Chromenones from Salicylaldehydes and Arylacetonitriles

An efficient and convenient protocol for the synthesis of 2H-chromenones has been developed. In the presence of (t)BuOK in DMF, good to excellent yields of various chromenones were obtained from the corresponding salicylaldehydes and arylacetonitriles. No protection of inert gas atmosphere is requir...

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Detalles Bibliográficos
Autores principales: Li, Chengcai, Zhu, Hailin, Zhang, Hang, Yang, Yongfeng, Wang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152355/
https://www.ncbi.nlm.nih.gov/pubmed/28718827
http://dx.doi.org/10.3390/molecules22071197
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author Li, Chengcai
Zhu, Hailin
Zhang, Hang
Yang, Yongfeng
Wang, Feng
author_facet Li, Chengcai
Zhu, Hailin
Zhang, Hang
Yang, Yongfeng
Wang, Feng
author_sort Li, Chengcai
collection PubMed
description An efficient and convenient protocol for the synthesis of 2H-chromenones has been developed. In the presence of (t)BuOK in DMF, good to excellent yields of various chromenones were obtained from the corresponding salicylaldehydes and arylacetonitriles. No protection of inert gas atmosphere is required here.
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spelling pubmed-61523552018-11-13 Synthesis of 2H-Chromenones from Salicylaldehydes and Arylacetonitriles Li, Chengcai Zhu, Hailin Zhang, Hang Yang, Yongfeng Wang, Feng Molecules Article An efficient and convenient protocol for the synthesis of 2H-chromenones has been developed. In the presence of (t)BuOK in DMF, good to excellent yields of various chromenones were obtained from the corresponding salicylaldehydes and arylacetonitriles. No protection of inert gas atmosphere is required here. MDPI 2017-07-18 /pmc/articles/PMC6152355/ /pubmed/28718827 http://dx.doi.org/10.3390/molecules22071197 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Li, Chengcai
Zhu, Hailin
Zhang, Hang
Yang, Yongfeng
Wang, Feng
Synthesis of 2H-Chromenones from Salicylaldehydes and Arylacetonitriles
title Synthesis of 2H-Chromenones from Salicylaldehydes and Arylacetonitriles
title_full Synthesis of 2H-Chromenones from Salicylaldehydes and Arylacetonitriles
title_fullStr Synthesis of 2H-Chromenones from Salicylaldehydes and Arylacetonitriles
title_full_unstemmed Synthesis of 2H-Chromenones from Salicylaldehydes and Arylacetonitriles
title_short Synthesis of 2H-Chromenones from Salicylaldehydes and Arylacetonitriles
title_sort synthesis of 2h-chromenones from salicylaldehydes and arylacetonitriles
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152355/
https://www.ncbi.nlm.nih.gov/pubmed/28718827
http://dx.doi.org/10.3390/molecules22071197
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AT yangyongfeng synthesisof2hchromenonesfromsalicylaldehydesandarylacetonitriles
AT wangfeng synthesisof2hchromenonesfromsalicylaldehydesandarylacetonitriles

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