Cargando…
Application of An Improved HPLC-FL Method to Screen Serine Palmitoyl Transferase Inhibitors
In this work, we reported the application and validation of an improved high-performance liquid chromatography method coupled with a fluorimetric detector (HPLC-FL) to screen the activity of two heterocyclic derivatives reported as serine palmitoyl transferase (SPT) inhibitors. The analytical condit...
Autores principales: | Bertini, Simone, Saccomanni, Giuseppe, Del Carlo, Sara, Digiacomo, Maria, Gargini, Claudia, Piano, Ilaria, Campisi, Giuseppe Matteo, Ghidoni, Riccardo, Macchia, Marco, Manera, Clementina |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152383/ https://www.ncbi.nlm.nih.gov/pubmed/28714922 http://dx.doi.org/10.3390/molecules22071198 |
Ejemplares similares
-
Design, Synthesis, and In Vitro Evaluation of Novel 8-Amino-Quinoline Combined with Natural Antioxidant Acids
por: Bacci, Andrea, et al.
Publicado: (2022) -
Traditional Uses of Cannabinoids and New Perspectives in the Treatment of Multiple Sclerosis
por: Gado, Francesca, et al.
Publicado: (2018) -
Regulation of serine palmitoyl-transferase and Rac1–Nox2 signaling in diabetic retinopathy
por: Alka, Kumari, et al.
Publicado: (2022) -
Intracellular APP Domain Regulates Serine-Palmitoyl-CoA Transferase Expression and Is Affected in Alzheimer's Disease
por: Grimm, Marcus O. W., et al.
Publicado: (2011) -
Using a biologically annotated library to analyze the anticancer mechanism of serine palmitoyl transferase (SPT) inhibitors
por: Sano, Osamu, et al.
Publicado: (2017)