Synthesis and Fungicidal Activity of 1-(Carbamoylmethyl)-2-aryl-3,1-benzoxazines

A series of new 1-(carbamoylmethyl)-2-aryl-3,1-benzoxazines were prepared in moderate to good yields by BF(3)·OEt(2)-catalyzed reactions of aromatic aldehydes with 2-(N-substituted carbamoylmethylamino)benzyl alcohols. The structures of the target compounds were confirmed by IR, (1)H-NMR, (13)C-NMR,...

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Detalles Bibliográficos
Autores principales: Tang, Zi-Long, Wang, Lian, Tan, Jing-Zhao, Wan, Yi-Chao, Jiao, Yin-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152388/
https://www.ncbi.nlm.nih.gov/pubmed/28684698
http://dx.doi.org/10.3390/molecules22071103
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author Tang, Zi-Long
Wang, Lian
Tan, Jing-Zhao
Wan, Yi-Chao
Jiao, Yin-Chun
author_facet Tang, Zi-Long
Wang, Lian
Tan, Jing-Zhao
Wan, Yi-Chao
Jiao, Yin-Chun
author_sort Tang, Zi-Long
collection PubMed
description A series of new 1-(carbamoylmethyl)-2-aryl-3,1-benzoxazines were prepared in moderate to good yields by BF(3)·OEt(2)-catalyzed reactions of aromatic aldehydes with 2-(N-substituted carbamoylmethylamino)benzyl alcohols. The structures of the target compounds were confirmed by IR, (1)H-NMR, (13)C-NMR, and elemental analyses. The fungicidal activities of the target compounds against plant fungi were preliminarily evaluated, and some of them exhibited good activity.
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spelling pubmed-61523882018-11-13 Synthesis and Fungicidal Activity of 1-(Carbamoylmethyl)-2-aryl-3,1-benzoxazines Tang, Zi-Long Wang, Lian Tan, Jing-Zhao Wan, Yi-Chao Jiao, Yin-Chun Molecules Article A series of new 1-(carbamoylmethyl)-2-aryl-3,1-benzoxazines were prepared in moderate to good yields by BF(3)·OEt(2)-catalyzed reactions of aromatic aldehydes with 2-(N-substituted carbamoylmethylamino)benzyl alcohols. The structures of the target compounds were confirmed by IR, (1)H-NMR, (13)C-NMR, and elemental analyses. The fungicidal activities of the target compounds against plant fungi were preliminarily evaluated, and some of them exhibited good activity. MDPI 2017-07-03 /pmc/articles/PMC6152388/ /pubmed/28684698 http://dx.doi.org/10.3390/molecules22071103 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Tang, Zi-Long
Wang, Lian
Tan, Jing-Zhao
Wan, Yi-Chao
Jiao, Yin-Chun
Synthesis and Fungicidal Activity of 1-(Carbamoylmethyl)-2-aryl-3,1-benzoxazines
title Synthesis and Fungicidal Activity of 1-(Carbamoylmethyl)-2-aryl-3,1-benzoxazines
title_full Synthesis and Fungicidal Activity of 1-(Carbamoylmethyl)-2-aryl-3,1-benzoxazines
title_fullStr Synthesis and Fungicidal Activity of 1-(Carbamoylmethyl)-2-aryl-3,1-benzoxazines
title_full_unstemmed Synthesis and Fungicidal Activity of 1-(Carbamoylmethyl)-2-aryl-3,1-benzoxazines
title_short Synthesis and Fungicidal Activity of 1-(Carbamoylmethyl)-2-aryl-3,1-benzoxazines
title_sort synthesis and fungicidal activity of 1-(carbamoylmethyl)-2-aryl-3,1-benzoxazines
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152388/
https://www.ncbi.nlm.nih.gov/pubmed/28684698
http://dx.doi.org/10.3390/molecules22071103
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AT tanjingzhao synthesisandfungicidalactivityof1carbamoylmethyl2aryl31benzoxazines
AT wanyichao synthesisandfungicidalactivityof1carbamoylmethyl2aryl31benzoxazines
AT jiaoyinchun synthesisandfungicidalactivityof1carbamoylmethyl2aryl31benzoxazines

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