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Live-cell imaging reveals the dynamics and function of single-telomere TERRA molecules in cancer cells

Telomeres cap the ends of eukaryotic chromosomes, protecting them from degradation and erroneous recombination events which may lead to genome instability. Telomeres are transcribed giving rise to telomeric repeat-containing RNAs, called TERRA. The TERRA long noncoding RNAs have been proposed to pla...

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Detalles Bibliográficos
Autores principales: Avogaro, Laura, Querido, Emmanuelle, Dalachi, Myriam, Jantsch, Michael F., Chartrand, Pascal, Cusanelli, Emilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152429/
https://www.ncbi.nlm.nih.gov/pubmed/29658398
http://dx.doi.org/10.1080/15476286.2018.1456300