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Structural and functional characterization of MBS301, an afucosylated bispecific anti-HER2 antibody

MBS301, a glyco-engineered bispecific anti-human epidermal growth factor receptor 2 (HER2) antibody with a typical IgG1 monoclonal antibody structure, was developed through dual-cell expression and in vitro assembling process. MBS301 consists of two half antibodies engineered from trastuzumab and pe...

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Detalles Bibliográficos
Autores principales:	Huang, Sijia, Li, Feng, Liu, Huifang, Ye, Pei, Fan, Xiaochuan, Yuan, Xinqiu, Wu, Zhidan, Chen, Jin, Jin, Chunyang, Shen, Beifen, Feng, Jiannan, Zhang, Boyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2018
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152455/ https://www.ncbi.nlm.nih.gov/pubmed/30081724 http://dx.doi.org/10.1080/19420862.2018.1486946

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