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Constitutive activation and overexpression of NF-κB/c-Rel in conjunction with p50 contribute to aggressive tongue tumorigenesis
Tongue squamous cell carcinoma (TSCC) is a most aggressive head and neck cancer often associated with a poor survival rate. Yet, it always shows better prognosis in presence of HPV16 infection. NF-κB plays a pivotal role in carcinogenesis and chemo-radio resistance of cancer but its role in tongue c...
Autores principales: | Gupta, Shilpi, Kumar, Prabhat, Kaur, Harsimrut, Sharma, Nishi, Gupta, Sunita, Saluja, Daman, Bharti, Alok C., Das, Bhudev |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152474/ https://www.ncbi.nlm.nih.gov/pubmed/30250646 http://dx.doi.org/10.18632/oncotarget.26041 |
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