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Exploring the association of legalisation status of cannabis with problematic cannabis use and impulsivity in the USA

BACKGROUND: There has been an increased trend towards the legalisation of medicinal and recreational cannabis use worldwide. This has been controversial as the long-term effects of frequent cannabis use on the brain are still poorly understood. METHODS: In this study, we investigated whether the leg...

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Autores principales: Destrée, Louise, Amiet, Danielle, Carter, Adrian, Lee, Rico, Lorenzetti, Valentina, Segrave, Rebecca, Youssef, George, Solowij, Nadia, Yücel, Murat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioExcel Publishing Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152614/
https://www.ncbi.nlm.nih.gov/pubmed/30263037
http://dx.doi.org/10.7573/dic.212541
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author Destrée, Louise
Amiet, Danielle
Carter, Adrian
Lee, Rico
Lorenzetti, Valentina
Segrave, Rebecca
Youssef, George
Solowij, Nadia
Yücel, Murat
author_facet Destrée, Louise
Amiet, Danielle
Carter, Adrian
Lee, Rico
Lorenzetti, Valentina
Segrave, Rebecca
Youssef, George
Solowij, Nadia
Yücel, Murat
author_sort Destrée, Louise
collection PubMed
description BACKGROUND: There has been an increased trend towards the legalisation of medicinal and recreational cannabis use worldwide. This has been controversial as the long-term effects of frequent cannabis use on the brain are still poorly understood. METHODS: In this study, we investigated whether the legal status of cannabis in the United States of America (USA) is associated with problematic cannabis use and impulsivity in 329 frequent cannabis users. The data were collected in 2015 and were analysed in 2017. Ethical approval for this study was obtained from Monash University in 2015. RESULTS: The results indicated that participants’ problematic cannabis use and impulsivity was not different whether they resided in states where cannabis is legal for medical and/or recreational use or prohibited. LIMITATIONS: The present study is a cross-sectional design, making it difficult to infer causality and establish whether cannabis use is a cause, consequence, or correlate of altered impulsivity. CONCLUSION: Our study supports the notion that frequent cannabis use is associated with impulsive behaviours, whilst, conversely, we did not find an association between US state legalisation and problematic cannabis use or impulsivity.
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spelling pubmed-61526142018-09-27 Exploring the association of legalisation status of cannabis with problematic cannabis use and impulsivity in the USA Destrée, Louise Amiet, Danielle Carter, Adrian Lee, Rico Lorenzetti, Valentina Segrave, Rebecca Youssef, George Solowij, Nadia Yücel, Murat Drugs Context Original Research BACKGROUND: There has been an increased trend towards the legalisation of medicinal and recreational cannabis use worldwide. This has been controversial as the long-term effects of frequent cannabis use on the brain are still poorly understood. METHODS: In this study, we investigated whether the legal status of cannabis in the United States of America (USA) is associated with problematic cannabis use and impulsivity in 329 frequent cannabis users. The data were collected in 2015 and were analysed in 2017. Ethical approval for this study was obtained from Monash University in 2015. RESULTS: The results indicated that participants’ problematic cannabis use and impulsivity was not different whether they resided in states where cannabis is legal for medical and/or recreational use or prohibited. LIMITATIONS: The present study is a cross-sectional design, making it difficult to infer causality and establish whether cannabis use is a cause, consequence, or correlate of altered impulsivity. CONCLUSION: Our study supports the notion that frequent cannabis use is associated with impulsive behaviours, whilst, conversely, we did not find an association between US state legalisation and problematic cannabis use or impulsivity. BioExcel Publishing Ltd 2018-09-17 /pmc/articles/PMC6152614/ /pubmed/30263037 http://dx.doi.org/10.7573/dic.212541 Text en Copyright © 2018 Destrée L, Amiet D, Carter A, Lee R, Lorenzetti V, Segrave R, Youssef G, Solowij N, Yücel M. Published by Drugs in Context under Creative Commons License Deed CC BY NC ND 4.0 which allows anyone to copy, distribute, and transmit the article provided it is properly attributed in the manner specified below. No commercial use without permission.
spellingShingle Original Research
Destrée, Louise
Amiet, Danielle
Carter, Adrian
Lee, Rico
Lorenzetti, Valentina
Segrave, Rebecca
Youssef, George
Solowij, Nadia
Yücel, Murat
Exploring the association of legalisation status of cannabis with problematic cannabis use and impulsivity in the USA
title Exploring the association of legalisation status of cannabis with problematic cannabis use and impulsivity in the USA
title_full Exploring the association of legalisation status of cannabis with problematic cannabis use and impulsivity in the USA
title_fullStr Exploring the association of legalisation status of cannabis with problematic cannabis use and impulsivity in the USA
title_full_unstemmed Exploring the association of legalisation status of cannabis with problematic cannabis use and impulsivity in the USA
title_short Exploring the association of legalisation status of cannabis with problematic cannabis use and impulsivity in the USA
title_sort exploring the association of legalisation status of cannabis with problematic cannabis use and impulsivity in the usa
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152614/
https://www.ncbi.nlm.nih.gov/pubmed/30263037
http://dx.doi.org/10.7573/dic.212541
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