Repositioning FDA Drugs as Potential Cruzain Inhibitors from Trypanosoma cruzi: Virtual Screening, In Vitro and In Vivo Studies

Chagas disease (CD) is a neglected disease caused by the parasite Trypanosoma cruzi, which affects underdeveloped countries. The current drugs of choice are nifurtimox and benznidazole, but both have severe adverse effects and less effectivity in chronic infections; therefore, the need to discover n...

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Detalles Bibliográficos
Autores principales: Palos, Isidro, Lara-Ramirez, Edgar E., Lopez-Cedillo, Julio Cesar, Garcia-Perez, Carlos, Kashif, Muhammad, Bocanegra-Garcia, Virgilio, Nogueda-Torres, Benjamin, Rivera, Gildardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152615/
https://www.ncbi.nlm.nih.gov/pubmed/28629155
http://dx.doi.org/10.3390/molecules22061015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152615/
https://www.ncbi.nlm.nih.gov/pubmed/28629155
http://dx.doi.org/10.3390/molecules22061015

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