Dichlorotrifluoromethoxyacetic Acid: Preparation and Reactivity †

We describe the first gram scale preparation of the reagent dichlorotrifluoromethoxyacetic acid. This stable compound is obtained in five steps starting from the cheap diethylene glycol. The reactivity of the sodium salt of this fluorinated acid was also tested and allowed the preparation of new ami...

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Detalles Bibliográficos
Autores principales: Zriba, Riadh, Desmarchelier, Alaric, Cadoret, Frédéric, Bouvet, Sébastien, Barthelemy, Anne-Laure, Pégot, Bruce, Diter, Patrick, Dagousset, Guillaume, Blazejewski, Jean-Claude, Anselmi, Elsa, Yagupolskii, Yurii, Magnier, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152670/
https://www.ncbi.nlm.nih.gov/pubmed/28598373
http://dx.doi.org/10.3390/molecules22060966
Descripción
Sumario:We describe the first gram scale preparation of the reagent dichlorotrifluoromethoxyacetic acid. This stable compound is obtained in five steps starting from the cheap diethylene glycol. The reactivity of the sodium salt of this fluorinated acid was also tested and allowed the preparation of new amides.

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