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Bioactive Natural Product and Superacid Chemistry for Lead Compound Identification: A Case Study of Selective hCA III and L-Type Ca(2+) Current Inhibitors for Hypotensive Agent Discovery
Dodoneine (Ddn) is one of the active compounds identified from Agelanthus dodoneifolius, which is a medicinal plant used in African pharmacopeia and traditional medicine for the treatment of hypertension. In the context of a scientific program aiming at discovering new hypotensive agents through the...
Autores principales: | Carreyre, Hélène, Carré, Grégoire, Ouedraogo, Maurice, Vandebrouck, Clarisse, Bescond, Jocelyn, Supuran, Claudiu T., Thibaudeau, Sébastien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152723/ https://www.ncbi.nlm.nih.gov/pubmed/28561785 http://dx.doi.org/10.3390/molecules22060915 |
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