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3D Pharmacophore-Based Virtual Screening and Docking Approaches toward the Discovery of Novel HPPD Inhibitors

p-Hydroxyphenylpyruvate dioxygenase (HPPD) is not only the useful molecular target in treating life-threatening tyrosinemia type I, but also an important target for chemical herbicides. A combined in silico structure-based pharmacophore and molecular docking-based virtual screening were performed to...

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Detalles Bibliográficos
Autores principales:	Fu, Ying, Sun, Yi-Na, Yi, Ke-Han, Li, Ming-Qiang, Cao, Hai-Feng, Li, Jia-Zhong, Ye, Fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152767/ https://www.ncbi.nlm.nih.gov/pubmed/28598377 http://dx.doi.org/10.3390/molecules22060959

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