Recent Advances in Asymmetric Organocatalyzed Conjugate Additions to Nitroalkenes

The asymmetric conjugate addition of carbon and heteroatom nucleophiles to nitroalkenes is a very interesting tool for the construction of highly functionalized synthetic building blocks. Thanks to the rapid development of asymmetric organocatalysis, significant progress has been made during the las...

Descripción completa

Detalles Bibliográficos
Autores principales: Alonso, Diego A., Baeza, Alejandro, Chinchilla, Rafael, Gómez, Cecilia, Guillena, Gabriela, Pastor, Isidro M., Ramón, Diego J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152790/
https://www.ncbi.nlm.nih.gov/pubmed/28555049
http://dx.doi.org/10.3390/molecules22060895
_version_ 1783357433817595904
author Alonso, Diego A.
Baeza, Alejandro
Chinchilla, Rafael
Gómez, Cecilia
Guillena, Gabriela
Pastor, Isidro M.
Ramón, Diego J.
author_facet Alonso, Diego A.
Baeza, Alejandro
Chinchilla, Rafael
Gómez, Cecilia
Guillena, Gabriela
Pastor, Isidro M.
Ramón, Diego J.
author_sort Alonso, Diego A.
collection PubMed
description The asymmetric conjugate addition of carbon and heteroatom nucleophiles to nitroalkenes is a very interesting tool for the construction of highly functionalized synthetic building blocks. Thanks to the rapid development of asymmetric organocatalysis, significant progress has been made during the last years in achieving efficiently this process, concerning chiral organocatalysts, substrates and reaction conditions. This review surveys the advances in asymmetric organocatalytic conjugate addition reactions to α,β-unsaturated nitroalkenes developed between 2013 and early 2017.
format Online
Article
Text
id pubmed-6152790
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-61527902018-11-13 Recent Advances in Asymmetric Organocatalyzed Conjugate Additions to Nitroalkenes Alonso, Diego A. Baeza, Alejandro Chinchilla, Rafael Gómez, Cecilia Guillena, Gabriela Pastor, Isidro M. Ramón, Diego J. Molecules Review The asymmetric conjugate addition of carbon and heteroatom nucleophiles to nitroalkenes is a very interesting tool for the construction of highly functionalized synthetic building blocks. Thanks to the rapid development of asymmetric organocatalysis, significant progress has been made during the last years in achieving efficiently this process, concerning chiral organocatalysts, substrates and reaction conditions. This review surveys the advances in asymmetric organocatalytic conjugate addition reactions to α,β-unsaturated nitroalkenes developed between 2013 and early 2017. MDPI 2017-05-29 /pmc/articles/PMC6152790/ /pubmed/28555049 http://dx.doi.org/10.3390/molecules22060895 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Alonso, Diego A.
Baeza, Alejandro
Chinchilla, Rafael
Gómez, Cecilia
Guillena, Gabriela
Pastor, Isidro M.
Ramón, Diego J.
Recent Advances in Asymmetric Organocatalyzed Conjugate Additions to Nitroalkenes
title Recent Advances in Asymmetric Organocatalyzed Conjugate Additions to Nitroalkenes
title_full Recent Advances in Asymmetric Organocatalyzed Conjugate Additions to Nitroalkenes
title_fullStr Recent Advances in Asymmetric Organocatalyzed Conjugate Additions to Nitroalkenes
title_full_unstemmed Recent Advances in Asymmetric Organocatalyzed Conjugate Additions to Nitroalkenes
title_short Recent Advances in Asymmetric Organocatalyzed Conjugate Additions to Nitroalkenes
title_sort recent advances in asymmetric organocatalyzed conjugate additions to nitroalkenes
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152790/
https://www.ncbi.nlm.nih.gov/pubmed/28555049
http://dx.doi.org/10.3390/molecules22060895
work_keys_str_mv AT alonsodiegoa recentadvancesinasymmetricorganocatalyzedconjugateadditionstonitroalkenes
AT baezaalejandro recentadvancesinasymmetricorganocatalyzedconjugateadditionstonitroalkenes
AT chinchillarafael recentadvancesinasymmetricorganocatalyzedconjugateadditionstonitroalkenes
AT gomezcecilia recentadvancesinasymmetricorganocatalyzedconjugateadditionstonitroalkenes
AT guillenagabriela recentadvancesinasymmetricorganocatalyzedconjugateadditionstonitroalkenes
AT pastorisidrom recentadvancesinasymmetricorganocatalyzedconjugateadditionstonitroalkenes
AT ramondiegoj recentadvancesinasymmetricorganocatalyzedconjugateadditionstonitroalkenes

Ejemplares similares