Phloroglucinols with Antioxidant Activities Isolated from Lysidice rhodostegia

Two new phloroglucinols, lysidisides X and Y (1 and 2), and two known compounds, 2-(2-methylbutyryl)phloroglucinol 1-O-β-d-glucopyranoside (3) and (E)-resveratrol 3-(6″-galloyl)-O-β-d-glucopyranoside (4), have been isolated from the roots of Lysidice rhodostegia. The structures of 1 and 2 were eluci...

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Autores principales: Wu, Xian-Fu, Li, Li, Li, Yong, Lv, Hai-Ning, Liu, Yun-Bao, Hu, You-Cai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152794/
https://www.ncbi.nlm.nih.gov/pubmed/28545244
http://dx.doi.org/10.3390/molecules22060855
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author Wu, Xian-Fu
Li, Li
Li, Yong
Lv, Hai-Ning
Liu, Yun-Bao
Hu, You-Cai
author_facet Wu, Xian-Fu
Li, Li
Li, Yong
Lv, Hai-Ning
Liu, Yun-Bao
Hu, You-Cai
author_sort Wu, Xian-Fu
collection PubMed
description Two new phloroglucinols, lysidisides X and Y (1 and 2), and two known compounds, 2-(2-methylbutyryl)phloroglucinol 1-O-β-d-glucopyranoside (3) and (E)-resveratrol 3-(6″-galloyl)-O-β-d-glucopyranoside (4), have been isolated from the roots of Lysidice rhodostegia. The structures of 1 and 2 were elucidated primarily by NMR experiments. Their absolute configurations were deduced via circular dichroism (CD) data and electronic circular dichroism (ECD) calculations. Compounds 1 and 2 exhibited significant antioxidative activities with IC(50) values of 12.0 and 11.8 µM, respectively.
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spelling pubmed-61527942018-11-13 Phloroglucinols with Antioxidant Activities Isolated from Lysidice rhodostegia Wu, Xian-Fu Li, Li Li, Yong Lv, Hai-Ning Liu, Yun-Bao Hu, You-Cai Molecules Article Two new phloroglucinols, lysidisides X and Y (1 and 2), and two known compounds, 2-(2-methylbutyryl)phloroglucinol 1-O-β-d-glucopyranoside (3) and (E)-resveratrol 3-(6″-galloyl)-O-β-d-glucopyranoside (4), have been isolated from the roots of Lysidice rhodostegia. The structures of 1 and 2 were elucidated primarily by NMR experiments. Their absolute configurations were deduced via circular dichroism (CD) data and electronic circular dichroism (ECD) calculations. Compounds 1 and 2 exhibited significant antioxidative activities with IC(50) values of 12.0 and 11.8 µM, respectively. MDPI 2017-05-23 /pmc/articles/PMC6152794/ /pubmed/28545244 http://dx.doi.org/10.3390/molecules22060855 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Wu, Xian-Fu
Li, Li
Li, Yong
Lv, Hai-Ning
Liu, Yun-Bao
Hu, You-Cai
Phloroglucinols with Antioxidant Activities Isolated from Lysidice rhodostegia
title Phloroglucinols with Antioxidant Activities Isolated from Lysidice rhodostegia
title_full Phloroglucinols with Antioxidant Activities Isolated from Lysidice rhodostegia
title_fullStr Phloroglucinols with Antioxidant Activities Isolated from Lysidice rhodostegia
title_full_unstemmed Phloroglucinols with Antioxidant Activities Isolated from Lysidice rhodostegia
title_short Phloroglucinols with Antioxidant Activities Isolated from Lysidice rhodostegia
title_sort phloroglucinols with antioxidant activities isolated from lysidice rhodostegia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152794/
https://www.ncbi.nlm.nih.gov/pubmed/28545244
http://dx.doi.org/10.3390/molecules22060855
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