Cargando…
Non-invasive measurement of mRNA decay reveals translation initiation as the major determinant of mRNA stability
The cytoplasmic abundance of mRNAs is strictly controlled through a balance of production and degradation. Whereas the control of mRNA synthesis through transcription has been well characterized, less is known about the regulation of mRNA turnover, and a consensus model explaining the wide variation...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152797/ https://www.ncbi.nlm.nih.gov/pubmed/30192227 http://dx.doi.org/10.7554/eLife.32536 |