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FGF2 crosstalk with Wnt signaling in mediating the anabolic action of PTH on bone formation

The mechanisms of the anabolic effect of parathyroid hormone (PTH) in bone are not fully defined. The bone anabolic effects of PTH require fibroblast growth factor 2 (FGF2) as well as Wnt signaling and FGF2 modulates Wnt signaling in osteoblasts. In vivo PTH administration differentially modulated W...

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Detalles Bibliográficos
Autores principales: Xiao, Liping, Fei, Yurong, Hurley, Marja M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152810/
https://www.ncbi.nlm.nih.gov/pubmed/30258857
http://dx.doi.org/10.1016/j.bonr.2018.09.003