DNA Vaccine–Induced Long-Lasting Cytotoxic T Cells Targeting Conserved Elements of Human Immunodeficiency Virus Gag Are Boosted Upon DNA or Recombinant Modified Vaccinia Ankara Vaccination

DNA-based vaccines able to induce efficient cytotoxic T-cell responses targeting conserved elements (CE) of human immunodeficiency virus type 1 (HIV-1) Gag have been developed. These CE were selected by stringent conservation, the ability to induce T-cell responses with broad human leukocyte antigen...

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Detalles Bibliográficos
Autores principales: Hu, Xintao, Valentin, Antonio, Cai, Yanhui, Dayton, Frances, Rosati, Margherita, Ramírez-Salazar, Eric G., Kulkarni, Viraj, Broderick, Kate E., Sardesai, Niranjan Y., Wyatt, Linda S., Earl, Patricia L., Moss, Bernard, Mullins, James I., Pavlakis, George N., Felber, Barbara K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152849/
https://www.ncbi.nlm.nih.gov/pubmed/29869530
http://dx.doi.org/10.1089/hum.2018.065

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