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Impact of MMP-2 and MMP-9 enzyme activity on wound healing, tumor growth and RACPP cleavage
Matrix metalloproteinases-2 and -9 (MMP-2/-9) are key tissue remodeling enzymes that have multiple overlapping activities critical for wound healing and tumor progression in vivo. To overcome issues of redundancy in studying their functions in vivo, we created MMP-2/-9 double knockout (DKO) mice in...
Autores principales: | Hingorani, Dina V., Lippert, Csilla N., Crisp, Jessica L., Savariar, Elamprakash N., Hasselmann, Jonathan P. C., Kuo, Christopher, Nguyen, Quyen T., Tsien, Roger Y., Whitney, Michael A., Ellies, Lesley G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152858/ https://www.ncbi.nlm.nih.gov/pubmed/30248101 http://dx.doi.org/10.1371/journal.pone.0198464 |
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