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Impact of MMP-2 and MMP-9 enzyme activity on wound healing, tumor growth and RACPP cleavage

Matrix metalloproteinases-2 and -9 (MMP-2/-9) are key tissue remodeling enzymes that have multiple overlapping activities critical for wound healing and tumor progression in vivo. To overcome issues of redundancy in studying their functions in vivo, we created MMP-2/-9 double knockout (DKO) mice in...

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Detalles Bibliográficos
Autores principales: Hingorani, Dina V., Lippert, Csilla N., Crisp, Jessica L., Savariar, Elamprakash N., Hasselmann, Jonathan P. C., Kuo, Christopher, Nguyen, Quyen T., Tsien, Roger Y., Whitney, Michael A., Ellies, Lesley G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152858/
https://www.ncbi.nlm.nih.gov/pubmed/30248101
http://dx.doi.org/10.1371/journal.pone.0198464

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