Cargando…
Differential binding of chemokines CXCL1, CXCL2 and CCL2 to mouse glomerular endothelial cells reveals specificity for distinct heparan sulfate domains
INTRODUCTION: Proliferative glomerulonephritis manifests in a range of renal diseases and is characterized by the influx of inflammatory cells into the glomerulus. Heparan sulfate (HS) is an important (co-)receptor for binding of chemokines, cytokines and leukocytes to the endothelial glycocalyx, a...
Autores principales: | van Gemst, J. J., Kouwenberg, M., Rops, A. L. W. M. M., van Kuppevelt, T. H., Berden, J. H., Rabelink, T. J., Loeven, M. A., van der Vlag, J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152867/ https://www.ncbi.nlm.nih.gov/pubmed/30248108 http://dx.doi.org/10.1371/journal.pone.0201560 |
Ejemplares similares
-
Blocking of inflammatory heparan sulfate domains by specific antibodies is not protective in experimental glomerulonephritis
por: van Gemst, Jasper J., et al.
Publicado: (2021) -
Glomerular endothelial glycocalyx-derived heparan sulfate inhibits glomerular leukocyte influx and attenuates experimental glomerulonephritis
por: Maciej-Hulme, Marissa L., et al.
Publicado: (2023) -
Synthetic heparan sulfate dodecasaccharides reveal single sulfation site interconverts CXCL8 and CXCL12 chemokine biology
por: Jayson, Gordon C., et al.
Publicado: (2015) -
Selective Binding of Heparin/Heparan Sulfate Oligosaccharides to Factor H and Factor H-Related Proteins: Therapeutic Potential for C3 Glomerulopathies
por: Loeven, Markus A., et al.
Publicado: (2021) -
RNA Contaminates Glycosaminoglycans Extracted from Cells and Tissues
por: van Gemst, Jasper J., et al.
Publicado: (2016)