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Improved Ribo-seq enables identification of cryptic translation events

Ribosome profiling has predicted thousands of short open reading frames (sORFs) in eukaryotic cells, but still suffers from substantial levels of noise. PRICE (https://github.com/erhard-lab/price) is a computational method modeling the experimental noise to accurately resolve overlapping sORFs and n...

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Detalles Bibliográficos
Autores principales: Erhard, Florian, Halenius, Anne, Zimmermann, Cosima, L’Hernault, Anne, Kowalewski, Daniel J., Weekes, Michael P., Stevanovic, Stefan, Zimmer, Ralf, Dölken, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152898/
https://www.ncbi.nlm.nih.gov/pubmed/29529017
http://dx.doi.org/10.1038/nmeth.4631