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Peptidomimetic inhibitors of L-plastin reduce the resorptive activity of osteoclast but not the bone forming activity of osteoblasts in vitro

Sealing ring formation is a requirement for osteoclast function. We have recently identified the role of an actin-bundling protein L-plastin in the assembly of nascent sealing zones (NSZs) at the early phase of sealing ring formation in osteoclasts. TNF-α signaling regulates this actin assembly by t...

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Detalles Bibliográficos
Autores principales:	Chellaiah, Meenakshi A., Majumdar, Sunipa, Aljohani, Hanan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152981/ https://www.ncbi.nlm.nih.gov/pubmed/30248139 http://dx.doi.org/10.1371/journal.pone.0204209

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