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Agonistic β-Klotho antibody mimics fibroblast growth factor 21 (FGF21) functions

Fibroblast growth factor 21 (FGF21), an endocrine hormone in the FGF family, plays a critical role in regulating metabolic homeostasis and has emerged as a therapeutic target for metabolic diseases, including Type 2 diabetes mellitus. FGF21 functions through a receptor complex that consists of an FG...

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Detalles Bibliográficos
Autores principales:	Min, Xiaoshan, Weiszmann, Jennifer, Johnstone, Sheree, Wang, Wei, Yu, Xinchao, Romanow, William, Thibault, Stephen, Li, Yang, Wang, Zhulun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2018
Materias:	Protein Structure and Folding
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153294/ https://www.ncbi.nlm.nih.gov/pubmed/30068552 http://dx.doi.org/10.1074/jbc.RA118.004343

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