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Malignant transformation of a urachal cyst—a case report and literature review
Urachal remnant diseases are very uncommon pathologies which are mostly benign. Rarely they can progress to a very aggressive form of Urachal cancer. The rarity of this condition has precluded large studies to help guide the diagnostic and therapeutic management of these potentially malignant lesion...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153322/ https://www.ncbi.nlm.nih.gov/pubmed/30271532 http://dx.doi.org/10.1093/jscr/rjy056 |
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author | Rhudd, Adrian Moghul, Masood Nair, Gopal McDonald, Jean |
author_facet | Rhudd, Adrian Moghul, Masood Nair, Gopal McDonald, Jean |
author_sort | Rhudd, Adrian |
collection | PubMed |
description | Urachal remnant diseases are very uncommon pathologies which are mostly benign. Rarely they can progress to a very aggressive form of Urachal cancer. The rarity of this condition has precluded large studies to help guide the diagnostic and therapeutic management of these potentially malignant lesions. In this case, a urachal cyst was discovered and conservative management was employed after a biopsy proved the lesion was benign. Unfortunately this patient represented several years later with a locally advanced urachal cancer. To date, this is the first clearly documented case of malignant transformation. The available literature surrounding these urachal cysts and cancers will be reviewed to determine if anything could have been done differently in this case and in the future should a similar case present. |
format | Online Article Text |
id | pubmed-6153322 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-61533222018-09-28 Malignant transformation of a urachal cyst—a case report and literature review Rhudd, Adrian Moghul, Masood Nair, Gopal McDonald, Jean J Surg Case Rep Case Report Urachal remnant diseases are very uncommon pathologies which are mostly benign. Rarely they can progress to a very aggressive form of Urachal cancer. The rarity of this condition has precluded large studies to help guide the diagnostic and therapeutic management of these potentially malignant lesions. In this case, a urachal cyst was discovered and conservative management was employed after a biopsy proved the lesion was benign. Unfortunately this patient represented several years later with a locally advanced urachal cancer. To date, this is the first clearly documented case of malignant transformation. The available literature surrounding these urachal cysts and cancers will be reviewed to determine if anything could have been done differently in this case and in the future should a similar case present. Oxford University Press 2018-03-27 /pmc/articles/PMC6153322/ /pubmed/30271532 http://dx.doi.org/10.1093/jscr/rjy056 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2018. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Case Report Rhudd, Adrian Moghul, Masood Nair, Gopal McDonald, Jean Malignant transformation of a urachal cyst—a case report and literature review |
title | Malignant transformation of a urachal cyst—a case report and literature review |
title_full | Malignant transformation of a urachal cyst—a case report and literature review |
title_fullStr | Malignant transformation of a urachal cyst—a case report and literature review |
title_full_unstemmed | Malignant transformation of a urachal cyst—a case report and literature review |
title_short | Malignant transformation of a urachal cyst—a case report and literature review |
title_sort | malignant transformation of a urachal cyst—a case report and literature review |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153322/ https://www.ncbi.nlm.nih.gov/pubmed/30271532 http://dx.doi.org/10.1093/jscr/rjy056 |
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