Cargando…
SPhyR: tumor phylogeny estimation from single-cell sequencing data under loss and error
MOTIVATION: Cancer is characterized by intra-tumor heterogeneity, the presence of distinct cell populations with distinct complements of somatic mutations, which include single-nucleotide variants (SNVs) and copy-number aberrations (CNAs). Single-cell sequencing technology enables one to study these...
| Autor principal: | |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153375/ https://www.ncbi.nlm.nih.gov/pubmed/30423070 http://dx.doi.org/10.1093/bioinformatics/bty589 |