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Brown tumor of the cervical spine in a patient with secondary hyperparathyroidism: A case report

INTRODUCTION: Brown tumors are non-neoplastic, expansive bone lesions that occur only in the setting of hyperparathyroidism. The most usual localization of brown tumors is in mandible, ribs and large bones. In cervical spine, to date, there are only 11 cases reported. The aim of this work is to repo...

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Autores principales: Sánchez-Calderón, Mauricio Daniel, Ochoa-Cacique, Diego, Medina Carrillo, Oscar, García González, Ulises, Vicuña González, Rosa María, Bravo Reyna, Carlos Cesar, Guerra-Mora, José Raúl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153394/
https://www.ncbi.nlm.nih.gov/pubmed/30245355
http://dx.doi.org/10.1016/j.ijscr.2018.09.023
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author Sánchez-Calderón, Mauricio Daniel
Ochoa-Cacique, Diego
Medina Carrillo, Oscar
García González, Ulises
Vicuña González, Rosa María
Bravo Reyna, Carlos Cesar
Guerra-Mora, José Raúl
author_facet Sánchez-Calderón, Mauricio Daniel
Ochoa-Cacique, Diego
Medina Carrillo, Oscar
García González, Ulises
Vicuña González, Rosa María
Bravo Reyna, Carlos Cesar
Guerra-Mora, José Raúl
author_sort Sánchez-Calderón, Mauricio Daniel
collection PubMed
description INTRODUCTION: Brown tumors are non-neoplastic, expansive bone lesions that occur only in the setting of hyperparathyroidism. The most usual localization of brown tumors is in mandible, ribs and large bones. In cervical spine, to date, there are only 11 cases reported. The aim of this work is to report the case of a patient with Wegener´s granulomatosis with secondary end stage renal failure who developed a brown tumor in C4 vertebra. PRESENTATION OF CASE: A 25-year-old woman with an history of 2 months of worsening cervicalgia without history of trauma. She complained about progressive neck pain with irradiation to both shoulders and right arm paresthesias, spontaneous fracture or brown spinal cord tumor were suspected. She presented cervical spine instability, was managed with corpectomy of C4 and biopsy. DISCUSSION: The initial suspicion of this disease must be since the first clinician contact of the patient and with the past medical history of end stage renal failure plus recent neurologic manifestations. The aim of neurosurgical management of these patients is to promote spinal stability and release spinal cord and nerve roots to eliminate risk of neurological deficits. CONCLUSION: The importance of the prompt diagnosis of the brown tumor is to establish a multidisciplinary management to prevent progression, neurologic complications and sequelae despite its benign behavior.
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spelling pubmed-61533942018-09-26 Brown tumor of the cervical spine in a patient with secondary hyperparathyroidism: A case report Sánchez-Calderón, Mauricio Daniel Ochoa-Cacique, Diego Medina Carrillo, Oscar García González, Ulises Vicuña González, Rosa María Bravo Reyna, Carlos Cesar Guerra-Mora, José Raúl Int J Surg Case Rep Article INTRODUCTION: Brown tumors are non-neoplastic, expansive bone lesions that occur only in the setting of hyperparathyroidism. The most usual localization of brown tumors is in mandible, ribs and large bones. In cervical spine, to date, there are only 11 cases reported. The aim of this work is to report the case of a patient with Wegener´s granulomatosis with secondary end stage renal failure who developed a brown tumor in C4 vertebra. PRESENTATION OF CASE: A 25-year-old woman with an history of 2 months of worsening cervicalgia without history of trauma. She complained about progressive neck pain with irradiation to both shoulders and right arm paresthesias, spontaneous fracture or brown spinal cord tumor were suspected. She presented cervical spine instability, was managed with corpectomy of C4 and biopsy. DISCUSSION: The initial suspicion of this disease must be since the first clinician contact of the patient and with the past medical history of end stage renal failure plus recent neurologic manifestations. The aim of neurosurgical management of these patients is to promote spinal stability and release spinal cord and nerve roots to eliminate risk of neurological deficits. CONCLUSION: The importance of the prompt diagnosis of the brown tumor is to establish a multidisciplinary management to prevent progression, neurologic complications and sequelae despite its benign behavior. Elsevier 2018-09-18 /pmc/articles/PMC6153394/ /pubmed/30245355 http://dx.doi.org/10.1016/j.ijscr.2018.09.023 Text en © 2018 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Sánchez-Calderón, Mauricio Daniel
Ochoa-Cacique, Diego
Medina Carrillo, Oscar
García González, Ulises
Vicuña González, Rosa María
Bravo Reyna, Carlos Cesar
Guerra-Mora, José Raúl
Brown tumor of the cervical spine in a patient with secondary hyperparathyroidism: A case report
title Brown tumor of the cervical spine in a patient with secondary hyperparathyroidism: A case report
title_full Brown tumor of the cervical spine in a patient with secondary hyperparathyroidism: A case report
title_fullStr Brown tumor of the cervical spine in a patient with secondary hyperparathyroidism: A case report
title_full_unstemmed Brown tumor of the cervical spine in a patient with secondary hyperparathyroidism: A case report
title_short Brown tumor of the cervical spine in a patient with secondary hyperparathyroidism: A case report
title_sort brown tumor of the cervical spine in a patient with secondary hyperparathyroidism: a case report
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153394/
https://www.ncbi.nlm.nih.gov/pubmed/30245355
http://dx.doi.org/10.1016/j.ijscr.2018.09.023
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