Analysis of bone healing with a novel bone wax substitute compared with bone wax in a porcine bone defect model

AIM: This pilot study describes a novel composite of hydroxyapatite and biodegradable polylactic acid with wax-like handling properties (BoneSeal(®)). The goal was to compare quantitative measures of bone healing between BoneSeal versus Bone wax. MATERIALS & METHODS: BoneSeal and Bone wax were i...

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Detalles Bibliográficos
Autores principales: Tham, Tristan, Roberts, Keith, Shanahan, John, Burban, John, Costantino, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2018
Materias:
Preliminary Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153452/
https://www.ncbi.nlm.nih.gov/pubmed/30271614
http://dx.doi.org/10.4155/fsoa-2018-0004
Descripción
Sumario:AIM: This pilot study describes a novel composite of hydroxyapatite and biodegradable polylactic acid with wax-like handling properties (BoneSeal(®)). The goal was to compare quantitative measures of bone healing between BoneSeal versus Bone wax. MATERIALS & METHODS: BoneSeal and Bone wax were introduced into separate defects of a single porcine specimen. After 6 weeks, the defect sites were harvested for analysis. RESULTS: Both groups had similar hemostatic action. The amount of new bone was significantly greater at 6 weeks in the BoneSeal group (38.05%) versus the Bone wax group (11.88%), p = 0.028. CONCLUSION: In this pilot study, BoneSeal had higher amounts of new bone formation compared with Bone wax.

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