Analysis of bone healing with a novel bone wax substitute compared with bone wax in a porcine bone defect model

AIM: This pilot study describes a novel composite of hydroxyapatite and biodegradable polylactic acid with wax-like handling properties (BoneSeal(®)). The goal was to compare quantitative measures of bone healing between BoneSeal versus Bone wax. MATERIALS & METHODS: BoneSeal and Bone wax were i...

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Autores principales: Tham, Tristan, Roberts, Keith, Shanahan, John, Burban, John, Costantino, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2018
Materias:
Preliminary Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153452/
https://www.ncbi.nlm.nih.gov/pubmed/30271614
http://dx.doi.org/10.4155/fsoa-2018-0004
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author Tham, Tristan
Roberts, Keith
Shanahan, John
Burban, John
Costantino, Peter
author_facet Tham, Tristan
Roberts, Keith
Shanahan, John
Burban, John
Costantino, Peter
author_sort Tham, Tristan
collection PubMed
description AIM: This pilot study describes a novel composite of hydroxyapatite and biodegradable polylactic acid with wax-like handling properties (BoneSeal(®)). The goal was to compare quantitative measures of bone healing between BoneSeal versus Bone wax. MATERIALS & METHODS: BoneSeal and Bone wax were introduced into separate defects of a single porcine specimen. After 6 weeks, the defect sites were harvested for analysis. RESULTS: Both groups had similar hemostatic action. The amount of new bone was significantly greater at 6 weeks in the BoneSeal group (38.05%) versus the Bone wax group (11.88%), p = 0.028. CONCLUSION: In this pilot study, BoneSeal had higher amounts of new bone formation compared with Bone wax.
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spelling pubmed-61534522018-09-28 Analysis of bone healing with a novel bone wax substitute compared with bone wax in a porcine bone defect model Tham, Tristan Roberts, Keith Shanahan, John Burban, John Costantino, Peter Future Sci OA Preliminary Communication AIM: This pilot study describes a novel composite of hydroxyapatite and biodegradable polylactic acid with wax-like handling properties (BoneSeal(®)). The goal was to compare quantitative measures of bone healing between BoneSeal versus Bone wax. MATERIALS & METHODS: BoneSeal and Bone wax were introduced into separate defects of a single porcine specimen. After 6 weeks, the defect sites were harvested for analysis. RESULTS: Both groups had similar hemostatic action. The amount of new bone was significantly greater at 6 weeks in the BoneSeal group (38.05%) versus the Bone wax group (11.88%), p = 0.028. CONCLUSION: In this pilot study, BoneSeal had higher amounts of new bone formation compared with Bone wax. Future Science Ltd 2018-07-26 /pmc/articles/PMC6153452/ /pubmed/30271614 http://dx.doi.org/10.4155/fsoa-2018-0004 Text en © 2018 Tham, Roberts, Shanahan, Burban, Costantino This work is licensed under a Creative Commons Attribution 4.0 License (http://creativecommons.org/licenses/by/4.0/)
spellingShingle Preliminary Communication
Tham, Tristan
Roberts, Keith
Shanahan, John
Burban, John
Costantino, Peter
Analysis of bone healing with a novel bone wax substitute compared with bone wax in a porcine bone defect model
title Analysis of bone healing with a novel bone wax substitute compared with bone wax in a porcine bone defect model
title_full Analysis of bone healing with a novel bone wax substitute compared with bone wax in a porcine bone defect model
title_fullStr Analysis of bone healing with a novel bone wax substitute compared with bone wax in a porcine bone defect model
title_full_unstemmed Analysis of bone healing with a novel bone wax substitute compared with bone wax in a porcine bone defect model
title_short Analysis of bone healing with a novel bone wax substitute compared with bone wax in a porcine bone defect model
title_sort analysis of bone healing with a novel bone wax substitute compared with bone wax in a porcine bone defect model
topic Preliminary Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153452/
https://www.ncbi.nlm.nih.gov/pubmed/30271614
http://dx.doi.org/10.4155/fsoa-2018-0004
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