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Mendelian randomization with a binary exposure variable: interpretation and presentation of causal estimates

Mendelian randomization uses genetic variants to make causal inferences about a modifiable exposure. Subject to a genetic variant satisfying the instrumental variable assumptions, an association between the variant and outcome implies a causal effect of the exposure on the outcome. Complications ari...

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Detalles Bibliográficos
Autores principales: Burgess, Stephen, Labrecque, Jeremy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153517/
https://www.ncbi.nlm.nih.gov/pubmed/30039250
http://dx.doi.org/10.1007/s10654-018-0424-6