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Mendelian randomization with a binary exposure variable: interpretation and presentation of causal estimates
Mendelian randomization uses genetic variants to make causal inferences about a modifiable exposure. Subject to a genetic variant satisfying the instrumental variable assumptions, an association between the variant and outcome implies a causal effect of the exposure on the outcome. Complications ari...
Autores principales: | Burgess, Stephen, Labrecque, Jeremy A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153517/ https://www.ncbi.nlm.nih.gov/pubmed/30039250 http://dx.doi.org/10.1007/s10654-018-0424-6 |
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