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The Role of α-sheet in Amyloid Oligomer Aggregation and Toxicity

A major barrier to developing effective treatments and diagnostics for amyloid diseases is the inability of traditional protein structure characterization methods to elucidate the structure of the toxic oligomers that form during amyloidogenesis. Some years ago, our lab “discovered” a novel protein...

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Detalles Bibliográficos
Autores principales: Bi, Timothy M., Daggett, Valerie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: YJBM 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153628/
https://www.ncbi.nlm.nih.gov/pubmed/30258312