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Extraction of Ejection Fraction from Echocardiography Notes for Constructing a Cohort of Patients having Heart Failure with reduced Ejection Fraction (HFrEF)
Left ventricular ejection fraction (LVEF) is an important prognostic indicator of cardiovascular outcomes. It is used clinically to determine the indication for several therapeutic interventions. LVEF is most commonly derived using in-line tools and some manual assessment by cardiologists from stand...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153777/ https://www.ncbi.nlm.nih.gov/pubmed/30255347 http://dx.doi.org/10.1007/s10916-018-1066-7 |
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author | Wagholikar, Kavishwar B. Fischer, Christina M. Goodson, Alyssa Herrick, Christopher D. Rees, Martin Toscano, Eloy MacRae, Calum A. Scirica, Benjamin M. Desai, Akshay S. Murphy, Shawn N. |
author_facet | Wagholikar, Kavishwar B. Fischer, Christina M. Goodson, Alyssa Herrick, Christopher D. Rees, Martin Toscano, Eloy MacRae, Calum A. Scirica, Benjamin M. Desai, Akshay S. Murphy, Shawn N. |
author_sort | Wagholikar, Kavishwar B. |
collection | PubMed |
description | Left ventricular ejection fraction (LVEF) is an important prognostic indicator of cardiovascular outcomes. It is used clinically to determine the indication for several therapeutic interventions. LVEF is most commonly derived using in-line tools and some manual assessment by cardiologists from standardized echocardiographic views. LVEF is typically documented in free-text reports, and variation in LVEF documentation pose a challenge for the extraction and utilization of LVEF in computer-based clinical workflows. To address this problem, we developed a computerized algorithm to extract LVEF from echocardiography reports for the identification of patients having heart failure with reduced ejection fraction (HFrEF) for therapeutic intervention at a large healthcare system. We processed echocardiogram reports for 57,158 patients with coded diagnosis of Heart Failure that visited the healthcare system over a two-year period. Our algorithm identified a total of 3910 patients with reduced ejection fraction. Of the 46,634 echocardiography reports processed, 97% included a mention of LVEF. Of these reports, 85% contained numerical ejection fraction values, 9% contained ranges, and the remaining 6% contained qualitative descriptions. Overall, 18% of extracted numerical LVEFs were ≤ 40%. Furthermore, manual validation for a sample of 339 reports yielded an accuracy of 1.0. Our study demonstrates that a regular expression-based approach can accurately extract LVEF from echocardiograms, and is useful for delineating heart-failure patients with reduced ejection fraction. |
format | Online Article Text |
id | pubmed-6153777 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-61537772018-10-04 Extraction of Ejection Fraction from Echocardiography Notes for Constructing a Cohort of Patients having Heart Failure with reduced Ejection Fraction (HFrEF) Wagholikar, Kavishwar B. Fischer, Christina M. Goodson, Alyssa Herrick, Christopher D. Rees, Martin Toscano, Eloy MacRae, Calum A. Scirica, Benjamin M. Desai, Akshay S. Murphy, Shawn N. J Med Syst Systems-Level Quality Improvement Left ventricular ejection fraction (LVEF) is an important prognostic indicator of cardiovascular outcomes. It is used clinically to determine the indication for several therapeutic interventions. LVEF is most commonly derived using in-line tools and some manual assessment by cardiologists from standardized echocardiographic views. LVEF is typically documented in free-text reports, and variation in LVEF documentation pose a challenge for the extraction and utilization of LVEF in computer-based clinical workflows. To address this problem, we developed a computerized algorithm to extract LVEF from echocardiography reports for the identification of patients having heart failure with reduced ejection fraction (HFrEF) for therapeutic intervention at a large healthcare system. We processed echocardiogram reports for 57,158 patients with coded diagnosis of Heart Failure that visited the healthcare system over a two-year period. Our algorithm identified a total of 3910 patients with reduced ejection fraction. Of the 46,634 echocardiography reports processed, 97% included a mention of LVEF. Of these reports, 85% contained numerical ejection fraction values, 9% contained ranges, and the remaining 6% contained qualitative descriptions. Overall, 18% of extracted numerical LVEFs were ≤ 40%. Furthermore, manual validation for a sample of 339 reports yielded an accuracy of 1.0. Our study demonstrates that a regular expression-based approach can accurately extract LVEF from echocardiograms, and is useful for delineating heart-failure patients with reduced ejection fraction. Springer US 2018-09-25 2018 /pmc/articles/PMC6153777/ /pubmed/30255347 http://dx.doi.org/10.1007/s10916-018-1066-7 Text en © The Author(s) 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Systems-Level Quality Improvement Wagholikar, Kavishwar B. Fischer, Christina M. Goodson, Alyssa Herrick, Christopher D. Rees, Martin Toscano, Eloy MacRae, Calum A. Scirica, Benjamin M. Desai, Akshay S. Murphy, Shawn N. Extraction of Ejection Fraction from Echocardiography Notes for Constructing a Cohort of Patients having Heart Failure with reduced Ejection Fraction (HFrEF) |
title | Extraction of Ejection Fraction from Echocardiography Notes for Constructing a Cohort of Patients having Heart Failure with reduced Ejection Fraction (HFrEF) |
title_full | Extraction of Ejection Fraction from Echocardiography Notes for Constructing a Cohort of Patients having Heart Failure with reduced Ejection Fraction (HFrEF) |
title_fullStr | Extraction of Ejection Fraction from Echocardiography Notes for Constructing a Cohort of Patients having Heart Failure with reduced Ejection Fraction (HFrEF) |
title_full_unstemmed | Extraction of Ejection Fraction from Echocardiography Notes for Constructing a Cohort of Patients having Heart Failure with reduced Ejection Fraction (HFrEF) |
title_short | Extraction of Ejection Fraction from Echocardiography Notes for Constructing a Cohort of Patients having Heart Failure with reduced Ejection Fraction (HFrEF) |
title_sort | extraction of ejection fraction from echocardiography notes for constructing a cohort of patients having heart failure with reduced ejection fraction (hfref) |
topic | Systems-Level Quality Improvement |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153777/ https://www.ncbi.nlm.nih.gov/pubmed/30255347 http://dx.doi.org/10.1007/s10916-018-1066-7 |
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