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Population Pharmacokinetics of the Antimalarial Amodiaquine: a Pooled Analysis To Optimize Dosing
Amodiaquine plus artesunate is the recommended antimalarial treatment in many countries where malaria is endemic. However, pediatric doses are largely based on a linear extrapolation from adult doses. We pooled data from previously published studies on the pharmacokinetics of amodiaquine, to optimiz...
Autores principales: | Ali, Ali Mohamed, Penny, Melissa A., Smith, Thomas A., Workman, Lesley, Sasi, Philip, Adjei, George O., Aweeka, Francesca, Kiechel, Jean-René, Jullien, Vincent, Rijken, Marcus J., McGready, Rose, Mwesigwa, Julia, Kristensen, Kim, Stepniewska, Kasia, Tarning, Joel, Barnes, Karen I., Denti, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153844/ https://www.ncbi.nlm.nih.gov/pubmed/30038039 http://dx.doi.org/10.1128/AAC.02193-17 |
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