Synthesis of Gibberellic Acid Derivatives and Their Effects on Plant Growth

A series of novel C-3-OH substituted gibberellin derivatives bearing an amide group were designed and synthesized from the natural product gibberellic acid (GA(3)). Their activities on the plant growth regulation of rice and Arabidopsis were evaluated in vivo. Among these compounds, 10d and 10f exhi...

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Detalles Bibliográficos
Autores principales: Tian, Hao, Xu, Yiren, Liu, Shaojin, Jin, Dingsha, Zhang, Jianjun, Duan, Liusheng, Tan, Weiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153925/
https://www.ncbi.nlm.nih.gov/pubmed/28445402
http://dx.doi.org/10.3390/molecules22050694
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author Tian, Hao
Xu, Yiren
Liu, Shaojin
Jin, Dingsha
Zhang, Jianjun
Duan, Liusheng
Tan, Weiming
author_facet Tian, Hao
Xu, Yiren
Liu, Shaojin
Jin, Dingsha
Zhang, Jianjun
Duan, Liusheng
Tan, Weiming
author_sort Tian, Hao
collection PubMed
description A series of novel C-3-OH substituted gibberellin derivatives bearing an amide group were designed and synthesized from the natural product gibberellic acid (GA(3)). Their activities on the plant growth regulation of rice and Arabidopsis were evaluated in vivo. Among these compounds, 10d and 10f exhibited appreciable inhibitory activities on rice (48.6% at 100 μmol/L) and Arabidopsis (41.4% at 100 μmol/L), respectively. These results provide new insights into the design and synthesis of potential plant growth regulators.
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spelling pubmed-61539252018-11-13 Synthesis of Gibberellic Acid Derivatives and Their Effects on Plant Growth Tian, Hao Xu, Yiren Liu, Shaojin Jin, Dingsha Zhang, Jianjun Duan, Liusheng Tan, Weiming Molecules Article A series of novel C-3-OH substituted gibberellin derivatives bearing an amide group were designed and synthesized from the natural product gibberellic acid (GA(3)). Their activities on the plant growth regulation of rice and Arabidopsis were evaluated in vivo. Among these compounds, 10d and 10f exhibited appreciable inhibitory activities on rice (48.6% at 100 μmol/L) and Arabidopsis (41.4% at 100 μmol/L), respectively. These results provide new insights into the design and synthesis of potential plant growth regulators. MDPI 2017-04-26 /pmc/articles/PMC6153925/ /pubmed/28445402 http://dx.doi.org/10.3390/molecules22050694 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Tian, Hao
Xu, Yiren
Liu, Shaojin
Jin, Dingsha
Zhang, Jianjun
Duan, Liusheng
Tan, Weiming
Synthesis of Gibberellic Acid Derivatives and Their Effects on Plant Growth
title Synthesis of Gibberellic Acid Derivatives and Their Effects on Plant Growth
title_full Synthesis of Gibberellic Acid Derivatives and Their Effects on Plant Growth
title_fullStr Synthesis of Gibberellic Acid Derivatives and Their Effects on Plant Growth
title_full_unstemmed Synthesis of Gibberellic Acid Derivatives and Their Effects on Plant Growth
title_short Synthesis of Gibberellic Acid Derivatives and Their Effects on Plant Growth
title_sort synthesis of gibberellic acid derivatives and their effects on plant growth
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153925/
https://www.ncbi.nlm.nih.gov/pubmed/28445402
http://dx.doi.org/10.3390/molecules22050694
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