Modification of Natural Eudesmane Scaffolds via Mizoroki-Heck Reactions

The Mizoroki-Heck reaction was applied to substrates derived from isocostic and ilicic acids, important sesquiterpene components of Dittrichia viscosa L. Greuter that were extracted directly from plant material collected in Morocco. After optimization of the metallo-catalysis conditions, various ary...

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Detalles Bibliográficos
Autores principales: Zaki, Mohamed, Akssira, Mohamed, Berteina-Raboin, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153938/
https://www.ncbi.nlm.nih.gov/pubmed/28425951
http://dx.doi.org/10.3390/molecules22040652
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author Zaki, Mohamed
Akssira, Mohamed
Berteina-Raboin, Sabine
author_facet Zaki, Mohamed
Akssira, Mohamed
Berteina-Raboin, Sabine
author_sort Zaki, Mohamed
collection PubMed
description The Mizoroki-Heck reaction was applied to substrates derived from isocostic and ilicic acids, important sesquiterpene components of Dittrichia viscosa L. Greuter that were extracted directly from plant material collected in Morocco. After optimization of the metallo-catalysis conditions, various aryl-groups were successfully introduced on the exocyclic double bond with an exclusive E-configuration and without racemization.
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spelling pubmed-61539382018-11-13 Modification of Natural Eudesmane Scaffolds via Mizoroki-Heck Reactions Zaki, Mohamed Akssira, Mohamed Berteina-Raboin, Sabine Molecules Article The Mizoroki-Heck reaction was applied to substrates derived from isocostic and ilicic acids, important sesquiterpene components of Dittrichia viscosa L. Greuter that were extracted directly from plant material collected in Morocco. After optimization of the metallo-catalysis conditions, various aryl-groups were successfully introduced on the exocyclic double bond with an exclusive E-configuration and without racemization. MDPI 2017-04-20 /pmc/articles/PMC6153938/ /pubmed/28425951 http://dx.doi.org/10.3390/molecules22040652 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zaki, Mohamed
Akssira, Mohamed
Berteina-Raboin, Sabine
Modification of Natural Eudesmane Scaffolds via Mizoroki-Heck Reactions
title Modification of Natural Eudesmane Scaffolds via Mizoroki-Heck Reactions
title_full Modification of Natural Eudesmane Scaffolds via Mizoroki-Heck Reactions
title_fullStr Modification of Natural Eudesmane Scaffolds via Mizoroki-Heck Reactions
title_full_unstemmed Modification of Natural Eudesmane Scaffolds via Mizoroki-Heck Reactions
title_short Modification of Natural Eudesmane Scaffolds via Mizoroki-Heck Reactions
title_sort modification of natural eudesmane scaffolds via mizoroki-heck reactions
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153938/
https://www.ncbi.nlm.nih.gov/pubmed/28425951
http://dx.doi.org/10.3390/molecules22040652
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