Cargando…

The Estimated Prevalence of Autism in School-Aged Children Living in Rural Nepal Using a Population-Based Screening Tool

Few data exist on the prevalence of autism in low-income countries. We translated, adapted and tested the acceptability of a Nepali-language version of a screening tool for autism (Autism Quotient-10). Using this tool, we estimated autism prevalence in 4098 rural Nepali children aged 9–13 years. Fou...

Descripción completa

Detalles Bibliográficos
Autores principales: Heys, Michelle, Gibbons, Felicity, Haworth, Ed, Medeiros, Emilie, Tumbahangphe, Kirti Man, Wickenden, Mary, Shrestha, Merina, Costello, Anthony, Manandhar, Dharma, Pellicano, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153945/
https://www.ncbi.nlm.nih.gov/pubmed/29855757
http://dx.doi.org/10.1007/s10803-018-3610-1
_version_ 1783357598822563840
author Heys, Michelle
Gibbons, Felicity
Haworth, Ed
Medeiros, Emilie
Tumbahangphe, Kirti Man
Wickenden, Mary
Shrestha, Merina
Costello, Anthony
Manandhar, Dharma
Pellicano, Elizabeth
author_facet Heys, Michelle
Gibbons, Felicity
Haworth, Ed
Medeiros, Emilie
Tumbahangphe, Kirti Man
Wickenden, Mary
Shrestha, Merina
Costello, Anthony
Manandhar, Dharma
Pellicano, Elizabeth
author_sort Heys, Michelle
collection PubMed
description Few data exist on the prevalence of autism in low-income countries. We translated, adapted and tested the acceptability of a Nepali-language version of a screening tool for autism (Autism Quotient-10). Using this tool, we estimated autism prevalence in 4098 rural Nepali children aged 9–13 years. Fourteen children scored > 6 out of 10, indicative of elevated autistic symptomatology, of which 13 also screened positive for disability. If the AQ-10 screening tool is as sensitive and specific in the Nepali population as it is in the UK, this would yield an estimated true prevalence of 3 in 1000 (95% confidence interval 2–5 in 1000). Future research is required to validate this tool through in-depth assessments of high-scoring children. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s10803-018-3610-1) contains supplementary material, which is available to authorized users.
format Online
Article
Text
id pubmed-6153945
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Springer US
record_format MEDLINE/PubMed
spelling pubmed-61539452018-10-04 The Estimated Prevalence of Autism in School-Aged Children Living in Rural Nepal Using a Population-Based Screening Tool Heys, Michelle Gibbons, Felicity Haworth, Ed Medeiros, Emilie Tumbahangphe, Kirti Man Wickenden, Mary Shrestha, Merina Costello, Anthony Manandhar, Dharma Pellicano, Elizabeth J Autism Dev Disord Original Paper Few data exist on the prevalence of autism in low-income countries. We translated, adapted and tested the acceptability of a Nepali-language version of a screening tool for autism (Autism Quotient-10). Using this tool, we estimated autism prevalence in 4098 rural Nepali children aged 9–13 years. Fourteen children scored > 6 out of 10, indicative of elevated autistic symptomatology, of which 13 also screened positive for disability. If the AQ-10 screening tool is as sensitive and specific in the Nepali population as it is in the UK, this would yield an estimated true prevalence of 3 in 1000 (95% confidence interval 2–5 in 1000). Future research is required to validate this tool through in-depth assessments of high-scoring children. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s10803-018-3610-1) contains supplementary material, which is available to authorized users. Springer US 2018-05-31 2018 /pmc/articles/PMC6153945/ /pubmed/29855757 http://dx.doi.org/10.1007/s10803-018-3610-1 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Paper
Heys, Michelle
Gibbons, Felicity
Haworth, Ed
Medeiros, Emilie
Tumbahangphe, Kirti Man
Wickenden, Mary
Shrestha, Merina
Costello, Anthony
Manandhar, Dharma
Pellicano, Elizabeth
The Estimated Prevalence of Autism in School-Aged Children Living in Rural Nepal Using a Population-Based Screening Tool
title The Estimated Prevalence of Autism in School-Aged Children Living in Rural Nepal Using a Population-Based Screening Tool
title_full The Estimated Prevalence of Autism in School-Aged Children Living in Rural Nepal Using a Population-Based Screening Tool
title_fullStr The Estimated Prevalence of Autism in School-Aged Children Living in Rural Nepal Using a Population-Based Screening Tool
title_full_unstemmed The Estimated Prevalence of Autism in School-Aged Children Living in Rural Nepal Using a Population-Based Screening Tool
title_short The Estimated Prevalence of Autism in School-Aged Children Living in Rural Nepal Using a Population-Based Screening Tool
title_sort estimated prevalence of autism in school-aged children living in rural nepal using a population-based screening tool
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153945/
https://www.ncbi.nlm.nih.gov/pubmed/29855757
http://dx.doi.org/10.1007/s10803-018-3610-1
work_keys_str_mv AT heysmichelle theestimatedprevalenceofautisminschoolagedchildrenlivinginruralnepalusingapopulationbasedscreeningtool
AT gibbonsfelicity theestimatedprevalenceofautisminschoolagedchildrenlivinginruralnepalusingapopulationbasedscreeningtool
AT haworthed theestimatedprevalenceofautisminschoolagedchildrenlivinginruralnepalusingapopulationbasedscreeningtool
AT medeirosemilie theestimatedprevalenceofautisminschoolagedchildrenlivinginruralnepalusingapopulationbasedscreeningtool
AT tumbahangphekirtiman theestimatedprevalenceofautisminschoolagedchildrenlivinginruralnepalusingapopulationbasedscreeningtool
AT wickendenmary theestimatedprevalenceofautisminschoolagedchildrenlivinginruralnepalusingapopulationbasedscreeningtool
AT shresthamerina theestimatedprevalenceofautisminschoolagedchildrenlivinginruralnepalusingapopulationbasedscreeningtool
AT costelloanthony theestimatedprevalenceofautisminschoolagedchildrenlivinginruralnepalusingapopulationbasedscreeningtool
AT manandhardharma theestimatedprevalenceofautisminschoolagedchildrenlivinginruralnepalusingapopulationbasedscreeningtool
AT pellicanoelizabeth theestimatedprevalenceofautisminschoolagedchildrenlivinginruralnepalusingapopulationbasedscreeningtool
AT heysmichelle estimatedprevalenceofautisminschoolagedchildrenlivinginruralnepalusingapopulationbasedscreeningtool
AT gibbonsfelicity estimatedprevalenceofautisminschoolagedchildrenlivinginruralnepalusingapopulationbasedscreeningtool
AT haworthed estimatedprevalenceofautisminschoolagedchildrenlivinginruralnepalusingapopulationbasedscreeningtool
AT medeirosemilie estimatedprevalenceofautisminschoolagedchildrenlivinginruralnepalusingapopulationbasedscreeningtool
AT tumbahangphekirtiman estimatedprevalenceofautisminschoolagedchildrenlivinginruralnepalusingapopulationbasedscreeningtool
AT wickendenmary estimatedprevalenceofautisminschoolagedchildrenlivinginruralnepalusingapopulationbasedscreeningtool
AT shresthamerina estimatedprevalenceofautisminschoolagedchildrenlivinginruralnepalusingapopulationbasedscreeningtool
AT costelloanthony estimatedprevalenceofautisminschoolagedchildrenlivinginruralnepalusingapopulationbasedscreeningtool
AT manandhardharma estimatedprevalenceofautisminschoolagedchildrenlivinginruralnepalusingapopulationbasedscreeningtool
AT pellicanoelizabeth estimatedprevalenceofautisminschoolagedchildrenlivinginruralnepalusingapopulationbasedscreeningtool