Acetaminophen reduces the protein levels of high affinity amino acid permeases and causes tryptophan depletion

In yeast, toxicity of acetaminophen (APAP), a frequently used analgesic and antipyretic drug, depends on ubiquitin-controlled processes. Previously, we showed a remarkable overlap in toxicity profiles between APAP and tyrosine, and a similarity with drugs like rapamycin and quinine, which induce deg...

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Detalles Bibliográficos
Autores principales: Huseinovic, Angelina, Dekker, Stefan J., Boogaard, Bob, Vermeulen, Nico. P. E., Kooter, Jan M., Vos, J. Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153950/
https://www.ncbi.nlm.nih.gov/pubmed/29978260
http://dx.doi.org/10.1007/s00726-018-2613-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153950/
https://www.ncbi.nlm.nih.gov/pubmed/29978260
http://dx.doi.org/10.1007/s00726-018-2613-8

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