Cargando…
Acetaminophen reduces the protein levels of high affinity amino acid permeases and causes tryptophan depletion
In yeast, toxicity of acetaminophen (APAP), a frequently used analgesic and antipyretic drug, depends on ubiquitin-controlled processes. Previously, we showed a remarkable overlap in toxicity profiles between APAP and tyrosine, and a similarity with drugs like rapamycin and quinine, which induce deg...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Vienna
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153950/ https://www.ncbi.nlm.nih.gov/pubmed/29978260 http://dx.doi.org/10.1007/s00726-018-2613-8 |