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Chromosome integrity checkpoints in stem and progenitor cells: transitions upon differentiation, pathogenesis, and aging
Loss of chromosome integrity is a major contributor to cancer. Checkpoints within the cell division cycle that facilitate the accuracy and outcome of chromosome segregation are thus critical pathways for preserving chromosome integrity and preventing chromosomal instability. The spindle assembly che...
Autores principales: | Brown, Andreas, Geiger, Hartmut |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154040/ https://www.ncbi.nlm.nih.gov/pubmed/30066086 http://dx.doi.org/10.1007/s00018-018-2891-z |
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