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Chromosome integrity checkpoints in stem and progenitor cells: transitions upon differentiation, pathogenesis, and aging

Loss of chromosome integrity is a major contributor to cancer. Checkpoints within the cell division cycle that facilitate the accuracy and outcome of chromosome segregation are thus critical pathways for preserving chromosome integrity and preventing chromosomal instability. The spindle assembly che...

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Detalles Bibliográficos
Autores principales: Brown, Andreas, Geiger, Hartmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154040/
https://www.ncbi.nlm.nih.gov/pubmed/30066086
http://dx.doi.org/10.1007/s00018-018-2891-z

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