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Cytotoxicity of α-Pyrrolidinophenones: an Impact of α-Aliphatic Side-chain Length and Changes in the Plasma Membrane Fluidity

Pyrovalerone derivatives (α-pyrrolidinophenones) form a branch of synthetic cathinones, a second most prominent group of novel psychoactive substances. Although the toxicity of 3,4-MDPV, a progenitor of the α-pyrrolidinophenones, is well described, little is known of the potential cytotoxicity of th...

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Detalles Bibliográficos
Autores principales: Wojcieszak, Jakub, Andrzejczak, Dariusz, Kedzierska, Marta, Milowska, Katarzyna, Zawilska, Jolanta B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154177/
https://www.ncbi.nlm.nih.gov/pubmed/29951896
http://dx.doi.org/10.1007/s12640-018-9923-1