Cargando…

Real-time corneal segmentation and 3D needle tracking in intrasurgical OCT

Ophthalmic procedures demand precise surgical instrument control in depth, yet standard operating microscopes supply limited depth perception. Current commercial microscope-integrated optical coherence tomography partially meets this need with manually-positioned cross-sectional images that offer qu...

Descripción completa

Detalles Bibliográficos
Autores principales: Keller, Brenton, Draelos, Mark, Tang, Gao, Farsiu, Sina, Kuo, Anthony N., Hauser, Kris, Izatt, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Optical Society of America 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154196/
https://www.ncbi.nlm.nih.gov/pubmed/30258685
http://dx.doi.org/10.1364/BOE.9.002716
_version_ 1783357656092639232
author Keller, Brenton
Draelos, Mark
Tang, Gao
Farsiu, Sina
Kuo, Anthony N.
Hauser, Kris
Izatt, Joseph A.
author_facet Keller, Brenton
Draelos, Mark
Tang, Gao
Farsiu, Sina
Kuo, Anthony N.
Hauser, Kris
Izatt, Joseph A.
author_sort Keller, Brenton
collection PubMed
description Ophthalmic procedures demand precise surgical instrument control in depth, yet standard operating microscopes supply limited depth perception. Current commercial microscope-integrated optical coherence tomography partially meets this need with manually-positioned cross-sectional images that offer qualitative estimates of depth. In this work, we present methods for automatic quantitative depth measurement using real-time, two-surface corneal segmentation and needle tracking in OCT volumes. We then demonstrate these methods for guidance of ex vivo deep anterior lamellar keratoplasty (DALK) needle insertions. Surgeons using the output of these methods improved their ability to reach a target depth, and decreased their incidence of corneal perforations, both with statistical significance. We believe these methods could increase the success rate of DALK and thereby improve patient outcomes.
format Online
Article
Text
id pubmed-6154196
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Optical Society of America
record_format MEDLINE/PubMed
spelling pubmed-61541962018-09-26 Real-time corneal segmentation and 3D needle tracking in intrasurgical OCT Keller, Brenton Draelos, Mark Tang, Gao Farsiu, Sina Kuo, Anthony N. Hauser, Kris Izatt, Joseph A. Biomed Opt Express Article Ophthalmic procedures demand precise surgical instrument control in depth, yet standard operating microscopes supply limited depth perception. Current commercial microscope-integrated optical coherence tomography partially meets this need with manually-positioned cross-sectional images that offer qualitative estimates of depth. In this work, we present methods for automatic quantitative depth measurement using real-time, two-surface corneal segmentation and needle tracking in OCT volumes. We then demonstrate these methods for guidance of ex vivo deep anterior lamellar keratoplasty (DALK) needle insertions. Surgeons using the output of these methods improved their ability to reach a target depth, and decreased their incidence of corneal perforations, both with statistical significance. We believe these methods could increase the success rate of DALK and thereby improve patient outcomes. Optical Society of America 2018-05-21 /pmc/articles/PMC6154196/ /pubmed/30258685 http://dx.doi.org/10.1364/BOE.9.002716 Text en © 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement © 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement (https://doi.org/10.1364/OA_License_v1)
spellingShingle Article
Keller, Brenton
Draelos, Mark
Tang, Gao
Farsiu, Sina
Kuo, Anthony N.
Hauser, Kris
Izatt, Joseph A.
Real-time corneal segmentation and 3D needle tracking in intrasurgical OCT
title Real-time corneal segmentation and 3D needle tracking in intrasurgical OCT
title_full Real-time corneal segmentation and 3D needle tracking in intrasurgical OCT
title_fullStr Real-time corneal segmentation and 3D needle tracking in intrasurgical OCT
title_full_unstemmed Real-time corneal segmentation and 3D needle tracking in intrasurgical OCT
title_short Real-time corneal segmentation and 3D needle tracking in intrasurgical OCT
title_sort real-time corneal segmentation and 3d needle tracking in intrasurgical oct
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154196/
https://www.ncbi.nlm.nih.gov/pubmed/30258685
http://dx.doi.org/10.1364/BOE.9.002716
work_keys_str_mv AT kellerbrenton realtimecornealsegmentationand3dneedletrackinginintrasurgicaloct
AT draelosmark realtimecornealsegmentationand3dneedletrackinginintrasurgicaloct
AT tanggao realtimecornealsegmentationand3dneedletrackinginintrasurgicaloct
AT farsiusina realtimecornealsegmentationand3dneedletrackinginintrasurgicaloct
AT kuoanthonyn realtimecornealsegmentationand3dneedletrackinginintrasurgicaloct
AT hauserkris realtimecornealsegmentationand3dneedletrackinginintrasurgicaloct
AT izattjosepha realtimecornealsegmentationand3dneedletrackinginintrasurgicaloct