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Effect of Tadalafil on Seizure Threshold and Activity of Antiepileptic Drugs in Three Acute Seizure Tests in Mice
Tadalafil, a selective phosphodiesterase type 5 inhibitor, is a long-acting oral agent for the treatment of erectile dysfunction of multiple etiologies. Although generalized tonic-clonic seizures were reported in a healthy man after taking tadalafil, the influence of tadalafil on seizure susceptibil...
Autores principales: | Socała, Katarzyna, Nieoczym, Dorota, Pieróg, Mateusz, Wyska, Elżbieta, Szafarz, Małgorzata, Doboszewska, Urszula, Wlaź, Piotr |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154210/ https://www.ncbi.nlm.nih.gov/pubmed/29427285 http://dx.doi.org/10.1007/s12640-018-9876-4 |
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